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. 2026 Apr 17;105(16):e48310. doi: 10.1097/MD.0000000000048310

Table 2.

Sensitivity analysis and expression quantitative trait loci mendelian randomization results of the 4 putative causal cytosine-phosphate-guanine sites.

CpG Gene Q-P Egger-P P
(depression)
Beta 95% CI
(depression)
P
(PTSD)
Beta 95% CI
(PTSD)
cg12317217 PCDHA2*
cg12661624 PTPRN2 0.70 .04 0.02 (0.0004–0.04) .67 −0.02 (−0.12 to 0.08)
cg24526596 DLGAP2* 0.62 0.92
cg00157656 ERICH1 .91 −0.001 (−0.03 to 0.03) .76 0.02 (−0.12 to 0.17)

CI = confidence interval, CpG = cytosine-phosphate-guanine, Egger-P = Mendelian randomization-Egger intercept test P-value, eQTL = expression quantitative trait loci, MR = Mendelian randomization, PTSD = post-traumatic stress disorder, Q-P = Cochran Q test P-value.

*

Indicates no available information from the eQTLGen consortium (phase I) for this gene.

Represents the eQTL MR analysis results.

Indicates statistical significance.