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. 2026 Mar 20;57(2):566–572. [Article in Chinese] doi: 10.12182/20260360104

表 4. The influence of hepatitis B virus on depression, anxiety, and quality of life in female patients.

乙型肝炎病毒对女性患者抑郁、焦虑及生活质量的影响

Group n SAS SDS Physiological function Social
function
Vitality Mental
health
Physiological function Emotional function Somatic
pain
Overall
health
 ULN: upper limit of normal; SAS: Self-Rating Anxiety Scale; SDS: Self-Rating Depression Scale. * P < 0.05, vs. low replication group; # P < 0.05, vs. medium replication group.
Control 30 26.35 ± 4.92 31.28 ± 5.51 90.15 ± 5.19 91.12 ± 5.98 91.12 ± 5.53 90.02 ± 5.01 89.92 ± 5.03 90.13 ± 4.03 91.26 ± 3.99 89.69 ± 5.09
ALT normal
 Low replication 33 27.98 ± 4.63 30.43 ± 5.89 89.36 ± 5.50 90.03 ± 6.26 90.94 ± 5.90 86.67 ± 4.97 88.31 ± 4.67 90.54 ± 3.82 93.03 ± 3.69 85.65 ± 5.23
 Medium replication 34 29.32 ± 6.08 28.97 ± 4.15 89.59 ± 5.15 89.37 ± 4.09 90.04 ± 3.78 87.64 ± 5.09 86.68 ± 5.03 90.04 ± 3.09 93.17 ± 3.65 85.57 ± 5.03
 High replication 30 29.28 ± 5.42 30.78 ± 4.93 90.98 ± 4.56 88.60 ± 4.34 91.95 ± 2.15 85.34 ± 4.55 88.61 ± 3.85 90.39 ± 5.45 91.82 ± 2.08 86.24 ± 3.84
 F 0.653 1.189 0.915 0.759 1.588 1.775 1.692 0.127 1.603 0.183
 P 0.523 0.309 0.404 0.471 0.210 0.175 0.190 0.881 0.207 0.833
ULN ≤ ALT < 2 ULN
 Low replication 31 38.05 ± 6.25 40.42 ± 9.55 85.15 ± 5.13 78.31 ± 8.36 85.20 ± 5.38 80.00 ± 6.82 79.56 ± 7.78 85.11 ± 6.89 81.29 ± 4.82 80.61 ± 7.43
 Medium replication 34 39.22 ± 5.80 41.21 ± 9.87 84.59 ± 5.27 78.88 ± 7.29 85.45 ± 5.19 79.84 ± 6.68 78.48 ± 6.49 85.23 ± 4.61 79.32 ± 4.60 79.35 ± 6..89
 High replication 34 39.92 ± 6.56 41.70 ± 8.54 86.26 ± 4.38 77.63 ± 8.25 85.12 ± 4.00 81.22 ± 6.40 77.61 ± 5.55 86.04 ± 5.20 79.14 ± 6.11 80.01 ± 6.96
 F 0.748 0.153 1.000 0.210 0.015 0.435 0.701 0.272 1.663 0.258
 P 0.476 0.858 0.372 0.811 0.985 0.649 0.499 0.763 0.195 0.773
2 ULN ≤ ALT
 Low replication 36 46.06 ± 4.92 44.14 ± 5.47 76.59 ± 6.21 70.69 ± 6.76 73.35 ± 6.25 71.97 ± 6.12 67.87 ± 6.81 70.37 ± 6.42 77.33 ± 6.31 78.71 ± 4.88
 Medium replication 38 56.42 ± 6.51* 54.92 ±4.51* 67.18 ± 6.54* 59.88 ± 5.11* 64.12 ± 6.16* 62.36 ± 6.67* 52.87 ± 5.07* 62.96 ± 6.00* 69.25 ± 5.65* 68.75 ± 3.70*
 High replication 36 64.66 ± 6.18*, # 67.08 ±4.57*, # 56.34 ± 7.60*, # 50.58 ± 8.28*, # 52.79 ± 7.93*, # 51.30 ± 5.62*, # 46.93 ± 7.74*, # 50.64 ± 6.61*, # 58.48 ± 4.77*, # 54.75 ± 5.67*, #
 F 89.231 200.602 79.849 78.676 82.112 101.096 96.257 88.939 116.193 226.569
 P < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001