Table 9.

Criteria for Initiating Early Anticonvulsant Prophylaxis. Prophylaxis should be maintained for 7 days.

Criteria for Initiating Early Anticonvulsant Prophylaxis	●Severe TBI ● Moderate or mild TBI that meets any of the following conditions: ○ Depressed skull fracture ○ Penetrating TBI ○ Intracranial bleeding ○ Post-traumatic seizure
Recommended Medications for Anticonvulsant Prophylaxis	Levetiracetam: 1 g every 12 h. Phenytoin: Initial loading dose of 15 mg/kg divided into 3 doses: (half at hour 0, a quarter at hour 8, and the last quarter at hour 16). The maintenance dose is 5 mg/kg/day divided into 3 daily doses.