Table 5.
Distribution of Adverse Drug Events (ADEs) by Medication Class and Specific Medication
| Drug Category | No. | % |
|---|---|---|
| Antihypertensive: | 33 | 27.3 |
| Atenolol | 7 | 5.8 |
| Nifedipine | 7 | 5.8 |
| Amlodipine | 5 | 4.1 |
| Diltiazem | 4 | 3.3 |
| Terazosin | 3 | 2.5 |
| Propranolol | 3 | 2.5 |
| Other | 7 | 5.8 |
| ACE inhibitor: | 25 | 20.7 |
| Lisinopril | 18 | 14.9 |
| Enalapril | 4 | 3.3 |
| Other | 4 | 3.3 |
| Antibiotic: | 10 | 8.3 |
| Trimethoprim | 3 | 2.5 |
| Other | 7 | 5.8 |
| Diuretic: | 9 | 7.4 |
| Furosemide | 4 | 3.3 |
| Triamterene | 4 | 3.3 |
| Hydrochlorothiazide | 1 | 0.8 |
| Anticoagulant: | 8 | 6.6 |
| Warfarin | 8 | 6.6 |
| Antidepressant: | 8 | 6.6 |
| Paroxeti | 3 | 2.5 |
| Other | 6 | 5.0 |
| Cardiovascular: | 8 | 6.6 |
| Digoxin | 8 | 6.6 |
| Cholesterol-lowering: | 6 | 5.0 |
| Lovastatin | 3 | 2.5 |
| Other | 3 | 2.5 |
| Pepticulcer: | 6 | 5.0 |
| Omeprazole | 3 | 2.5 |
| Ranitidine | 3 | 2.5 |
| NSAID: | 6 | 5.0 |
| Ibuprofen | 2 | 1.7 |
| Naproxen | 2 | 1.7 |
| Other | 3 | 2.5 |
| Antiseizure: | 4 | 3.3 |
| Phenytoin | 4 | 3.3 |
| Carbamazepine | 1 | 0.8 |
| Other | 16 | 13.2 |
Note: There were 121 ADEs; many ADEs were associated with more than one drug category. In addition, within categories, ADEs were sometimes associated with more than one medication, so that the numbers for subcategories may sum to more than the total for a category. In all, 68 (56.2 percent) of the ADEs were associated with one or more drugs from the following classes: antihypertensives, ACE inhibitors, antibiotics and diuretics.