Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Activation and inhibition of QTCL and wild type
Assays were in the forward direction (assay C) using standard reaction conditions
| Mutant
|
3-PGA | Pi |
|---|---|---|
| Ka | Ki | |
| Wild typea | 0.17 ± 0.015 | 2.96 ± 0.12 |
| QTCL | 0.11 ± 0.013 | 2.62 ± 0.10 |
| MPa | 0.03 ± 0.008 | 12.28 ± 0.73 |
| MP-QTCL | 0.10 ± 0.014 | 2.87 ± 0.08 |
Data were previously published in Boehlein et al. (2005). Ki for phosphate was determined in the presence of 2.5 mm 3-PGA.
