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Modeling analysis of Chlamydomonas wild-type and mutant FKB12s. A, Amino acid substitutions performed in the M52V E54Q and M52K G53Q mutants compared to wild-type FKB12. Schematic diagrams of wild-type FKB12 (B), and the M52V E54Q (C) and M52K G53Q (D) mutants showing protein-rapamycin interactions. Data were generated using the LIGPLOT program (Wallace et al., 1995).
