Figure 3.

Motif characterization for genetic, congruence, and protein networks. A. Both transitive and intransitive motifs are enriched in the genetic network, tetrad4 and tetrad6 for the asymmetric network and triad2, tetrad1 and tetrad4 for the symmetric network. Only transitive motifs are enriched in congruence and protein networks, triad2 and tetrad6 for symmetric and asymmetric congruence networks, triad2, tetrad3, and tetrad6 for the protein network. Motif enrichment criteria are as defined in [17] (see Methods). B. The connections between triangle and square motifs in the symmetric genetic network. Three types of relationships exist between triangles and squares and the percentage of each scenario is labeled. The red numbers indicate individual pathways.