Table 7.

Relationship between hotspots for the rapid breakdown of linkage disequilibrium and chromosomal organization

	CEU sample		YRI sample		CHB+JPT sample
	Hotspots	Other intervals	Hotspots	Other intervals	Hotspots	Other intervals
Number of intervals	14,525	702,099	15,623	750,857	12,607	610,826
Chromosome organization
Within 5 Mb of centromere	325	471**	324	460**	282	464**
Within 10 Mb of centromere	965	1124**	942	1127**	933	1115**
Within 15 Mb of centromere	1715	1804	1647	1816**	1685	1798*
Within 5 Mb of telomere	795	352**	879	336**	766	347**
Within 10 Mb of telomere	1642	773**	1793	746**	1635	765**
Within 15 Mb of telomere	2219	1179**	2425	1138**	2273	1170**
Within 5 Mb of heterochromatin	195	271**	202	273**	182	269**
Within 10 Mb of heterochromatin	553	694**	575	700**	558	700**
Within 15 Mb of heterochromatin	1057	1153*	1041	1159*	1077	1160
Large genomic duplications	85	137**	107	133*	78	129**
Large genomic duplications (cis)	41	81**	53	78*	43	75**
Large genomic duplications (trans)	47	67*	62	65	40	62*

^*Hotspots and other intervals differ significantly at P < 0.001 level.

^**Hotspots and other intervals differ significantly at P < 0.000001 level.