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. 2026 Apr 10;14:1724454. doi: 10.3389/fped.2026.1724454

Table 3.

Differences between serious group and non-serious group.

Characteristics Total Non-serious Serious p Corrected pe
n = 231 n = 194 n = 37
Age (year) 6.08 (3.52) 6.21 (3.53) 5.44 (3.42) 0.227 >1.000
Height (cm) 115.5 (23.9) 116.5 (23.8) 110.5 (23.7) 0.872 >1.000
Weight (kg) 22.3 (11.9) 22.8 (12.2) 19.3 (10.0) 0.106 >1.000
Gender 0.698 >1.000
 Male 156 130 26
 Female 75 64 11
The time from initiation of transfusion to the TRAR (min) 55 (40–85) 57.5 (40–90) 50 (35–75) 0.284 >1.000
Symptom resolution time (min) 38 (25–70) 35.5 (25–70) 40 (30–90) 0.521 >1.000
Hospitalization days (day) 17 (6–29) 17 (5.7–29) 22 (8.5–33) 0.260 >1.000
Type of TRAR
 Allergic reaction 221 187 34 0.218a >1.000
 FNHTR 8 6 2
 Others 2 1 1
Blood group 0.419b >1.000
 O 95 82 13
 A 69 58 11
 B 48 37 11
 AB 19 17 2
Type of blood product 0.011c 0.165
 PLT 174 140 34
 FFP 34 32 2
 BRC 17 16 1
 Cryoprecipitate 6 6 0
PLTd 0.623 >1.000
 Fresh 132 109 20
 Stored 42 31 14
Transfusion history 0.282 >1.000
 Yes 192 159 33
 No 39 35 4
History of TRAR 0.482 >1.000
 Yes 88 72 16
 No 143 122 21
Allergy history 0.048 0.720
 Yes 74 57 17
 No 157 137 20
Prophylactic administration before transfusion 0.000 0.000
 Yes 104 77 27
 No 127 117 10
a

Difference of allergic reaction and non allergic reaction between serious group and non-serious group.

b

Difference of O and non O between serious group and non-serious group.

c

Difference of PLT and non PLT between serious group and non-serious group.

d

We define PLT collected ≤72 h as fresh PLT and platelets collected >72 h as stored PLT.

e

Bonferroni-corrected significance level = 0.0033. P-values were compared against this threshold.