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. 2026 Apr 10;6:1798348. doi: 10.3389/fradi.2026.1798348

Table 6.

The statistical analysis of KL-grade-based KOA classification and MOAKS score prediction using trabecular parameters from different regression methods.

Methods Metrics Radiomic-based (CT) CNN (CT) CT-SMA (CT) CNN (MR)
KL-grade-based KOA classification Precision 0.689 ± 0.078 0.745 ± 0.041 0.863 ± 0.053 0.887 ± 0.061
Recall 0.773 ± 0.045 0.794 ± 0.047 0.903 ± 0.068 0.935 ± 0.037
F1 score 0.738 ± 0.057 0.763 ± 0.040 0.879 ± 0.056 0.910 ± 0.044
AUC 0.742 ± 0.032 0.778 ± 0.044 0.883 ± 0.029 0.914 ± 0.048
MOAKS score prediction Mean Average Error 1.438 ± 0.153 1.059 ± 0.072 0.893 ± 0.041 0.876 ± 0.038
R-Square 0.723 ± 0.129 0.790 ± 0.064 0.881 ± 0.037 0.903 ± 0.030

The classification is implemented using regressed trabecular parameters on image patches as features. Here we compare different methods to obtain trabecular parameters and the employed aggregation for different methods is Transformer layers. We compare radiomic-based method, CNN-based method and our proposed CT-SMA on CT images. Results of CNN-based method on MR images are provided in the right column for references.

Bold values indicate the best performance among the CT-based methods.