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. 2005 Dec 9;33(22):6953–6960. doi: 10.1093/nar/gki995

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© The Author 2005. Published by Oxford University Press. All rights reserved

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Graphical representation of decay parameters showing that there is no base-flipping signal when AP is opposite or adjacent to the target base. (a) Plot of A factor versus lifetime for the crystalline complexes APadj–M.HhaI–AdoHcy (squares) and APopp–M.HhaI–AdoHcy (diamonds), in comparison with APout–M.HhaI–AdoHcy (triangles). (b) Plot of A factors versus lifetimes for the solution phase systems APadj free duplex (open triangles); APadj ternary complex (closed triangles); APopp free duplex (open squares); and APopp ternary complex (closed squares).