Table 1.
Selected demographic, exposure, and outcome variables by ALAD, eNOS, and VDR genotype in 798 Korean lead workers.a
|
ALAD |
eNOS |
VDR |
||||
|---|---|---|---|---|---|---|
| Characteristic | 1–1 | 1–2 | Glu/Glu | Asp/Glu or Asp/Asp | bb | Bb or BB |
| No. (%) | 716 (90.1) | 79 (9.9) | 673 (84.9) | 120 (15.1) | 709 (88.8) | 89 (11.2) |
| Sex n (%) | ||||||
| Male | 569 (79.5) | 62 (78.5) | 537 (79.8) | 93 (77.5) | 572 (80.7) | 62 (69.7) |
| Female | 147 (20.5) | 17 (21.5) | 136 (20.2) | 27 (22.5) | 137 (19.3) | 27 (30.3) |
| Alcohol use, n (%) | ||||||
| No previous alcohol | 207 (29.0) | 24 (30.4) | 201 (30.0) | 30 (25.0) | 208 (29.4) | 23 (25.8) |
| Current use | 466 (65.2) | 49 (62.0) | 429 (63.8) | 84 (70.0) | 456 (64.4) | 62 (69.7) |
| Past use | 42 (5.9) | 6 (7.6) | 42 (6.3) | 6 (5.0) | 44 (6.2) | 4 (4.5) |
| BMI (kg/m2) | 23.1 ± 3.0 | 22.3 ± 2.6 | 23.1 ± 3.0 | 22.7 ± 2.8 | 22.9 ± 2.9 | 23.9 ± 3.4 |
| Age (years) | 40.5 ± 10.2 | 40.1 ± 9.7 | 40.3 ± 10.1 | 41.1 ± 10.1 | 40.2 ± 10.1 | 42.7 ± 10.3 |
| Systolic blood pressure (mm Hg) | 123.4 ± 16.5 | 122.3 ± 14.5 | 123.4 ± 16.5 | 122.7 ± 15.5 | 122.6 ± 15.6 | 129.1 ± 20.6 |
| Blood lead (μg/dL) | 31.7 ± 14.9 | 34.2 ± 15.9 | 32.0 ± 15.1 | 31.2 ± 14.6 | 31.6 ± 14.8 | 34.8 ± 16.1 |
| Tibia lead (μg Pb/g bone mineral) | 37.5 ± 40.6 | 31.4 ± 29.5 | 37.5 ± 41.6 | 35.8 ± 34.0 | 37.1 ± 41.2 | 38.1 ± 33.5 |
| DMSA-chelatable lead (μg Pb/mg creatinine) | 0.76 ± 0.82 | 0.84 ± 1.19 | 0.78 ± 0.90 | 0.72 ± 0.62 | 0.75 ± 0.87 | 0.93 ± 0.76 |
| Uric acid (mg/dL) | 4.8 ± 1.2 | 4.6 ± 1.1 | 4.9 ± 1.2 | 4.6 ± 1.1 | 4.8 ± 1.2 | 4.7 ± 1.1 |
| Serum creatinine (mg/dL) | 0.90 ± 0.15 | 0.86 ± 0.12 | 0.90 ± 0.16 | 0.89 ± 0.13 | 0.90 ± 0.16 | 0.89 ± 0.13 |
ALAD, eNOS, and VDR genotyping were completed on 795, 793, and 798 lead workers, respectively. Modified from Weaver et al. (2003b).
a
Values are mean ± SD unless otherwise noted.