Table 1. Cyb2p activity affects lactate and pyruvate concentrations of transgenic animals.

Strain	Cyb2p†	Lactate, mM	Pyruvate, mM	Lactate/pyruvate ratio
N2	ND	2.43 ± 0.51	0.148 ± 0.026	16.4 ± 4.5
N2 + Pnuo-1::CYB2	3.9 ± 1.4	1.95 ± 0.18	0.117 ± 0.010	16.7 ± 2.1
N2 + Plet-858::CYB2	3.8 ± 1.1	1.92 ± 0.12	0.114 ± 0.011	16.8 ± 1.9
LB25	ND	3.06 ± 0.32	0.063 ± 0.007	48.6 ± 7.4
LB25 + Pnuo-1::CYB2	4.2 ± 1.6	2.36 ± 0.12*	0.068 ± 0.003	34.7 ± 2.5*
LB25 + Plet-858::CYB2	6.8 ± 2.7	2.00 ± 0.17*	0.062 ± 0.004	32.3 ± 3.4*
LB27	ND	4.23 ± 0.75	0.052 ± 0.004	81.3 ± 15.6
LB27 + Pnuo-1::CYB2	7.3 ± 2.2	3.03 ± 0.13	0.076 ± 0.007*	39.9 ± 4.0*
LB27 + Plet-858::CYB2	8.4 ± 3.0	2.37 ± 0.53*	0.063 ± 0.007	37.6 ± 9.3*

The values reported are the means ± SD of a minimum of four determinations. *, P < 0.05, compared with corresponding parental strain by using a two-sample t test. ND, not detected.

^†Cyb2p activity was measured as l-lactate-dependent cytochrome c reductase activity. The values reported are nanomoles of cytochrome c per minute per milligram of protein.