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. 2026 Apr 19;31(8):1341. doi: 10.3390/molecules31081341
Cx Connexins
HCs hemichannels
Cx43 Connexin 43
p-Cx43 phosphorylated connexin 43
TBI traumatic brain injury
SCI spinal cord injury
PNI peripheral nerve injury
Cx36 Connexin 36
Cx32 Connexin 32
Cx47 Connexin 47
Cx30 Connexin 30
Cx29 Connexin 29
Cx26 Connexin 26
Cx37 Connexin 37
Cx40 Connexin 40
Cx45 Connexin 45
Cx50 Connexin 50
GJs Gap junctions
CL intracellular loop
NTH N-terminal helices
CSD cortical spreading depolarization
NVU Neurovascular unit
MCAO middle cerebral artery occlusion
pMCAO permanent MCAO
dMCAO distal MCAO
OGD-R oxygen–glucose deprivation/re-oxygenation
ICH intracerebral hemorrhage
SAH subarachnoid hemorrhage
NO nitric oxide
PKC protein kinase C
CBX carbenoxolone
AS-ODN antisense oligodeoxynucleotides
siRNA small interfering RNA
ERK1/2 extracellular signal-regulated kinase 1/2
PI3K phosphoinositide 3-kinase
BBB blood–brain barrier
AQP4 aquaporin-4
MLKL mixed lineage kinase domain-like protein
SVZ subventricular zone
rtPA recombinant tissue plasminogen activator
SNP single nucleotide polymorphism
PNS peripheral nervous system
CNS central nervous system
EE enriched environment
TNF-α tumor necrosis factor-α
TLR4 Toll-like receptor 4
YAP Yes-associated protein
CRTC1 CREB-regulated transcription coactivator 1
H/R hypoxia/re-oxygenation
hUCB human umbilical cord blood cells
TXL Tongxinluo
BMP2/4 bone morphogenetic proteins 2/4
BMSCs bone marrow stromal cells
NPCs neural progenitor cells
GFAP glial fibrillary acidic protein
ACKR3 atypical chemokine receptor 3
I/R ischemia/reperfusion
CVS cerebral vasospasm
BCAS bilateral carotid artery stenosis
GAD67 glutamate decarboxylase 67
α7-nAChR α7 nicotinic acetylcholine receptor
NOS nitric oxide synthases
VHL Von Hippel–Lindau
S368 serine 368
PTZ pentylenetetrazol
ROS reactive oxygen species
GLT-1 glutamate transporter-1
LPS lipopolysaccharide
NAC N-acetylcysteine
GSH glutathione
MDA malondialdehyde
ATP adenosine triphosphate
OxATP oxidized ATP
LTP long-term potentiation
3-MA 3-methyladenine
NSCs neural stem cells
αCT1 α-connexin carboxyl-terminal peptide
CCI cortical impact
FPI fluid percussion injury
GJA1-20K 20-kDa isoform of gap junction alpha-1 protein
GS-Rb1 ginsenoside Rb1
H2 molecular hydrogen
NSPCs neural stem/progenitor cells
P2X7 purinergic receptor P2X7
mTOR mechanistic target of rapamycin
SLC7A11 solute carrier family 7 member 11
GPX4 glutathione peroxidase 4
4-HNE 4-hydroxynonenal
HBO hyperbaric oxygen therapy
HF-rTMS high-frequency repetitive transcranial magnetic stimulation
Sig-1R sigma-1 receptor
GlyT2 glycine transporter 2
VEGF vascular endothelial growth factor
epSPCs ependymal spinal cord progenitor cells
DRG dorsal root ganglion
SGCs satellite glial cells
BDNF brain-derived neurotrophic factor
miR-1 microRNA-1
NLRP3 NOD-like receptor family pyrin domain-containing 3
SARM1 sterile alpha and TIR motif-containing protein 1
PSNL partial sciatic nerve ligation
SNL spinal nerve ligation
CFA complete Freund’s adjuvant
CIPN chemotherapy-induced peripheral neuropathy
COMP-Ang1 cartilage oligomeric matrix protein–angiopoietin-1
TRPA1 transient receptor potential ankyrin 1
GluK2 ionotropic kainate receptor 2
IMPs intramembranous particles
MAM mitochondrial-associated membrane
A2AR adenosine A2A receptors
AD Alzheimer’s disease
amyloid-beta
MFN2 mitofusin-2
ApoE Apolipoprotein E
OPCs Oligodendrocyte progenitor cells
CD73 ecto-5′-nucleotidase
4-PBA 4-phenylbutyric acid
PD Parkinson’s disease
SNpc Substantia nigra pars compacta
α-syn α-synuclein
MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
6-OHDA 6-hydroxydopamine
GDNF glial cell line-derived neurotrophic factor
bFGF basic fibroblast growth factor
EGFR epidermal growth factor receptor
LID levodopa-induced dyskinesia
PV+ parvalbumin-positive
ENK+ enkephalin-positive
Ca2+ calcium ion
ALS Amyotrophic lateral sclerosis
SOD1 superoxide dismutase 1
SOD1-G93A glycine-to-alanine substitution at position 93 of SOD1
GJA1 Gap junction protein alpha 1
EAAT2 Excitatory amino acid transporter 2
iPSC induced pluripotent stem cell
GAP19 Connexin 43 hemichannel inhibitory peptide
HD Huntington’s disease
mHTT mutant huntingtin
PolyQ Polyglutamine expansion
CN caudate nucleus
GP globus pallidus
GSK-3β glycogen synthase kinase 3 beta
JAK2 Janus kinase 2
CORT corticosterone
STAT3 Signal transducer and activator of transcription 3
IL interleukin
CUS chronic unpredictable stress
PFC prefrontal cortex
CSDS chronic social defeat stress
BD Bipolar disorder
ZTP zotepine
Akt protein kinase B
CACNA1C calcium voltage-gated channel subunit alpha1 C
Sox9 SRY-box transcription factor 9
ACC anterior cingulate cortex