| Cx | Connexins |
| HCs | hemichannels |
| Cx43 | Connexin 43 |
| p-Cx43 | phosphorylated connexin 43 |
| TBI | traumatic brain injury |
| SCI | spinal cord injury |
| PNI | peripheral nerve injury |
| Cx36 | Connexin 36 |
| Cx32 | Connexin 32 |
| Cx47 | Connexin 47 |
| Cx30 | Connexin 30 |
| Cx29 | Connexin 29 |
| Cx26 | Connexin 26 |
| Cx37 | Connexin 37 |
| Cx40 | Connexin 40 |
| Cx45 | Connexin 45 |
| Cx50 | Connexin 50 |
| GJs | Gap junctions |
| CL | intracellular loop |
| NTH | N-terminal helices |
| CSD | cortical spreading depolarization |
| NVU | Neurovascular unit |
| MCAO | middle cerebral artery occlusion |
| pMCAO | permanent MCAO |
| dMCAO | distal MCAO |
| OGD-R | oxygen–glucose deprivation/re-oxygenation |
| ICH | intracerebral hemorrhage |
| SAH | subarachnoid hemorrhage |
| NO | nitric oxide |
| PKC | protein kinase C |
| CBX | carbenoxolone |
| AS-ODN | antisense oligodeoxynucleotides |
| siRNA | small interfering RNA |
| ERK1/2 | extracellular signal-regulated kinase 1/2 |
| PI3K | phosphoinositide 3-kinase |
| BBB | blood–brain barrier |
| AQP4 | aquaporin-4 |
| MLKL | mixed lineage kinase domain-like protein |
| SVZ | subventricular zone |
| rtPA | recombinant tissue plasminogen activator |
| SNP | single nucleotide polymorphism |
| PNS | peripheral nervous system |
| CNS | central nervous system |
| EE | enriched environment |
| TNF-α | tumor necrosis factor-α |
| TLR4 | Toll-like receptor 4 |
| YAP | Yes-associated protein |
| CRTC1 | CREB-regulated transcription coactivator 1 |
| H/R | hypoxia/re-oxygenation |
| hUCB | human umbilical cord blood cells |
| TXL | Tongxinluo |
| BMP2/4 | bone morphogenetic proteins 2/4 |
| BMSCs | bone marrow stromal cells |
| NPCs | neural progenitor cells |
| GFAP | glial fibrillary acidic protein |
| ACKR3 | atypical chemokine receptor 3 |
| I/R | ischemia/reperfusion |
| CVS | cerebral vasospasm |
| BCAS | bilateral carotid artery stenosis |
| GAD67 | glutamate decarboxylase 67 |
| α7-nAChR | α7 nicotinic acetylcholine receptor |
| NOS | nitric oxide synthases |
| VHL | Von Hippel–Lindau |
| S368 | serine 368 |
| PTZ | pentylenetetrazol |
| ROS | reactive oxygen species |
| GLT-1 | glutamate transporter-1 |
| LPS | lipopolysaccharide |
| NAC | N-acetylcysteine |
| GSH | glutathione |
| MDA | malondialdehyde |
| ATP | adenosine triphosphate |
| OxATP | oxidized ATP |
| LTP | long-term potentiation |
| 3-MA | 3-methyladenine |
| NSCs | neural stem cells |
| αCT1 | α-connexin carboxyl-terminal peptide |
| CCI | cortical impact |
| FPI | fluid percussion injury |
| GJA1-20K | 20-kDa isoform of gap junction alpha-1 protein |
| GS-Rb1 | ginsenoside Rb1 |
| H2 | molecular hydrogen |
| NSPCs | neural stem/progenitor cells |
| P2X7 | purinergic receptor P2X7 |
| mTOR | mechanistic target of rapamycin |
| SLC7A11 | solute carrier family 7 member 11 |
| GPX4 | glutathione peroxidase 4 |
| 4-HNE | 4-hydroxynonenal |
| HBO | hyperbaric oxygen therapy |
| HF-rTMS | high-frequency repetitive transcranial magnetic stimulation |
| Sig-1R | sigma-1 receptor |
| GlyT2 | glycine transporter 2 |
| VEGF | vascular endothelial growth factor |
| epSPCs | ependymal spinal cord progenitor cells |
| DRG | dorsal root ganglion |
| SGCs | satellite glial cells |
| BDNF | brain-derived neurotrophic factor |
| miR-1 | microRNA-1 |
| NLRP3 | NOD-like receptor family pyrin domain-containing 3 |
| SARM1 | sterile alpha and TIR motif-containing protein 1 |
| PSNL | partial sciatic nerve ligation |
| SNL | spinal nerve ligation |
| CFA | complete Freund’s adjuvant |
| CIPN | chemotherapy-induced peripheral neuropathy |
| COMP-Ang1 | cartilage oligomeric matrix protein–angiopoietin-1 |
| TRPA1 | transient receptor potential ankyrin 1 |
| GluK2 | ionotropic kainate receptor 2 |
| IMPs | intramembranous particles |
| MAM | mitochondrial-associated membrane |
| A2AR | adenosine A2A receptors |
| AD | Alzheimer’s disease |
| Aβ | amyloid-beta |
| MFN2 | mitofusin-2 |
| ApoE | Apolipoprotein E |
| OPCs | Oligodendrocyte progenitor cells |
| CD73 | ecto-5′-nucleotidase |
| 4-PBA | 4-phenylbutyric acid |
| PD | Parkinson’s disease |
| SNpc | Substantia nigra pars compacta |
| α-syn | α-synuclein |
| MPTP | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| 6-OHDA | 6-hydroxydopamine |
| GDNF | glial cell line-derived neurotrophic factor |
| bFGF | basic fibroblast growth factor |
| EGFR | epidermal growth factor receptor |
| LID | levodopa-induced dyskinesia |
| PV+ | parvalbumin-positive |
| ENK+ | enkephalin-positive |
| Ca2+ | calcium ion |
| ALS | Amyotrophic lateral sclerosis |
| SOD1 | superoxide dismutase 1 |
| SOD1-G93A | glycine-to-alanine substitution at position 93 of SOD1 |
| GJA1 | Gap junction protein alpha 1 |
| EAAT2 | Excitatory amino acid transporter 2 |
| iPSC | induced pluripotent stem cell |
| GAP19 | Connexin 43 hemichannel inhibitory peptide |
| HD | Huntington’s disease |
| mHTT | mutant huntingtin |
| PolyQ | Polyglutamine expansion |
| CN | caudate nucleus |
| GP | globus pallidus |
| GSK-3β | glycogen synthase kinase 3 beta |
| JAK2 | Janus kinase 2 |
| CORT | corticosterone |
| STAT3 | Signal transducer and activator of transcription 3 |
| IL | interleukin |
| CUS | chronic unpredictable stress |
| PFC | prefrontal cortex |
| CSDS | chronic social defeat stress |
| BD | Bipolar disorder |
| ZTP | zotepine |
| Akt | protein kinase B |
| CACNA1C | calcium voltage-gated channel subunit alpha1 C |
| Sox9 | SRY-box transcription factor 9 |
| ACC | anterior cingulate cortex |