| HIV | Human immunodeficiency virus |
| SSA | Sub-Saharan Africa |
| HIV-1C | Human immunodeficiency virus type 1 subtype C |
| ART | Antiretroviral therapy |
| LMICs | Low- and middle-income countries |
| PWH | People with HIV |
| HIV-1B | Human immunodeficiency virus type 1 subtype B |
| RT | Reverse transcriptase |
| NRTIs | Nucleoside reverse transcriptase inhibitors |
| NNRTIs | Non-nucleoside reverse transcriptase inhibitors |
| NRTTIs | Nucleoside reverse transcriptase translocation inhibitors |
| RTIs | Reverse transcriptase inhibitors |
| RT-conn | Reverse transcriptase connection |
| RNase H | Ribonuclease H |
| DRMs | Drug resistance mutations |
| NVP | Nevirapine |
| DLV | Delavirdine |
| TN | Treatment-naïve |
| TE | Treatment-experienced |
| VF | Virologic failure |
| BCPP | Botswana Combination Prevention Project |
| EFV | Efavirenz |
| DTG | Dolutegravir |
| NGS | Next-generation sequencing |
| RNA | Ribonucleic acid |
| DNA | Deoxyribonucleic acid |
| VL | Viral load |
| VS | Virally suppressed |
| MSA | Multiple-sequence alignment |
| IQRs | Interquartile ranges |