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. 1995;93:281–314.

Diagnostic pars plana vitrectomy report of a 21-year retrospective study.

G N Palexas 1, W R Green 1, M F Goldberg 1, Y Ding 1
PMCID: PMC1312062  PMID: 8719683

Abstract

PURPOSE: To review the experience of diagnostic pars plana vitrectomies (PPV). METHODS: The authors reviewed 405 consecutive diagnostic PPV's performed between November 1973 and October 1994. RESULTS: Diagnostic vitrectomy was performed in 215 (53%) of 405 eyes for suspected endophthalmitis. Of those 215 cases, acute inflammation was confirmed in 62 (28.8%), 60 (27.9%) had microbial organisms present and 36 (16.7%) were culture-positive. Microbial organisms were observed microscopically in 31 (20%) of 156 patients suspected of postoperative endophthalmitis. Of those 31 cases, 23 (74%) were gram-positive, eleven (37%) of 30 eyes had organisms associated with glaucoma filtering procedures and 20 (16%) of 126 eyes had organisms with non-filtering procedures. The pooled percentage of eyes that developed postoperative endophthalmitis as a complication during the period July 1990 thru June 1994 is 5 (0.046%) out of a heterogeneous group of 10,898 cases operated on at the Wilmer Eye Institute for cataract, glaucoma, corneal transplant, pars plana vitrectomy and retinal detachment. Bacteria were identified microscopically in 6 (18%) of 34 post-traumatic cases. Microbial organisms were identified in 23 (92%) of 25 cases with an endogenous infection. Patients with endogenous infections had the most fungal infections, and the majority were in males. Neoplasms were diagnosed in 58 (14%) of the 405 cases. The most common neoplasm was ocular lymphoma 42 (72%), 69% of which were in females. Only 42 (48.3%) of 87 patients clinically suspected of having ocular lymphoma, actually had ocular lymphoma. Those negative for lymphoma were significantly older (67.4 +/- 10 years) compared to those with lymphoma (60.4 +/- 14 years) (P = 0.01). CONCLUSION: Diagnostic PPV has proved to be valuable in confirming and establishing various clinical diagnoses.

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Selected References

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  1. Affeldt J. C., Flynn H. W., Jr, Forster R. K., Mandelbaum S., Clarkson J. G., Jarus G. D. Microbial endophthalmitis resulting from ocular trauma. Ophthalmology. 1987 Apr;94(4):407–413. doi: 10.1016/s0161-6420(87)33447-5. [DOI] [PubMed] [Google Scholar]
  2. Aguilar G. L., Blumenkrantz M. S., Egbert P. R., McCulley J. P. Candida endophthalmitis after intravenous drug abuse. Arch Ophthalmol. 1979 Jan;97(1):96–100. doi: 10.1001/archopht.1979.01020010036008. [DOI] [PubMed] [Google Scholar]
  3. Aiello L. P., Javitt J. C., Canner J. K. National outcomes of penetrating keratoplasty. Risks of endophthalmitis and retinal detachment. Arch Ophthalmol. 1993 Apr;111(4):509–513. doi: 10.1001/archopht.1993.01090040101041. [DOI] [PubMed] [Google Scholar]
  4. Alfaro D. V., Roth D., Liggett P. E. Posttraumatic endophthalmitis. Causative organisms, treatment, and prevention. Retina. 1994;14(3):206–211. [PubMed] [Google Scholar]
  5. Apple D. J., Mamalis N., Steinmetz R. L., Loftfield K., Olson R. J., Notz R. G. Phacoanaphylactic endophthalmitis following ECCE and IOL implantation. J Am Intraocul Implant Soc. 1984 Fall;10(4):423–424. doi: 10.1016/s0146-2776(84)80039-7. [DOI] [PubMed] [Google Scholar]
  6. Augsburger J. J. Invasive diagnostic techniques for uveitis and simulating conditions. Trans Pa Acad Ophthalmol Otolaryngol. 1990;42:964–971. [PubMed] [Google Scholar]
  7. Bacon A. S., Davison C. R., Patel B. C., Frazer D. G., Ficker L. A., Dart J. K. Infective endophthalmitis following vitreoretinal surgery. Eye (Lond) 1993;7(Pt 4):529–534. doi: 10.1038/eye.1993.115. [DOI] [PubMed] [Google Scholar]
  8. Banerjee S. N., Emori T. G., Culver D. H., Gaynes R. P., Jarvis W. R., Horan T., Edwards J. R., Tolson J., Henderson T., Martone W. J. Secular trends in nosocomial primary bloodstream infections in the United States, 1980-1989. National Nosocomial Infections Surveillance System. Am J Med. 1991 Sep 16;91(3B):86S–89S. doi: 10.1016/0002-9343(91)90349-3. [DOI] [PubMed] [Google Scholar]
  9. Barr C. C., Green W. R., Payne J. W., Knox D. L., Jensen A. D., Thompson R. L. Intraocular reticulum-cell sarcoma: clinico-pathologic study of four cases and review of the literature. Surv Ophthalmol. 1975 Jan-Feb;19(4):224–239. [PubMed] [Google Scholar]
  10. Beck-Sagué C., Jarvis W. R. Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990. National Nosocomial Infections Surveillance System. J Infect Dis. 1993 May;167(5):1247–1251. doi: 10.1093/infdis/167.5.1247. [DOI] [PubMed] [Google Scholar]
  11. Bloch-Michel E., Nussenblatt R. B. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol. 1987 Feb 15;103(2):234–235. doi: 10.1016/s0002-9394(14)74235-7. [DOI] [PubMed] [Google Scholar]
  12. Bodoia R. D., Kinyoun J. L., Lou Q. L., Bunt-Milam A. H. Aspergillus necrotizing retinitis. A clinico-pathologic study and review. Retina. 1989;9(3):226–231. [PubMed] [Google Scholar]
  13. Boldt H. C., Pulido J. S., Blodi C. F., Folk J. C., Weingeist T. A. Rural endophthalmitis. Ophthalmology. 1989 Dec;96(12):1722–1726. doi: 10.1016/s0161-6420(89)32658-3. [DOI] [PubMed] [Google Scholar]
  14. Brinton G. S., Topping T. M., Hyndiuk R. A., Aaberg T. M., Reeser F. H., Abrams G. W. Posttraumatic endophthalmitis. Arch Ophthalmol. 1984 Apr;102(4):547–550. doi: 10.1001/archopht.1984.01040030425016. [DOI] [PubMed] [Google Scholar]
  15. Brooks R. G. Prospective study of Candida endophthalmitis in hospitalized patients with candidemia. Arch Intern Med. 1989 Oct;149(10):2226–2228. [PubMed] [Google Scholar]
  16. Brown S. M., Jampol L. M., Cantrill H. L. Intraocular lymphoma presenting as retinal vasculitis. Surv Ophthalmol. 1994 Sep-Oct;39(2):133–140. doi: 10.1016/0039-6257(94)90158-9. [DOI] [PubMed] [Google Scholar]
  17. Bruner W. E., Green W. R., Stark W. J. A case of epithelial ingrowth primarily involving the lens capsule. Ophthalmic Surg. 1986 Aug;17(8):483–485. [PubMed] [Google Scholar]
  18. Cameron M. E., Forster T. D. Endophthalmitis occurring during hospitalization following cataract surgery. Ophthalmic Surg. 1978 Oct;9(5):52–57. [PubMed] [Google Scholar]
  19. Carroll D. M., Franklin R. M. Vitreous biopsy in uveitis of unknown cause. Retina. 1981;1(3):245–251. doi: 10.1097/00006982-198101030-00022. [DOI] [PubMed] [Google Scholar]
  20. Christy N. E., Lall P. Postoperative endophthalmitis following cataract surgery. Effects on subconjunctival antibiotics and other factrs. Arch Ophthalmol. 1973 Nov;90(5):361–366. doi: 10.1001/archopht.1973.01000050363005. [DOI] [PubMed] [Google Scholar]
  21. Collyer R. Reticulum cell sarcoma of eye and orbit. Can J Ophthalmol. 1972 Apr;7(2):247–249. [PubMed] [Google Scholar]
  22. Davey R. T., Jr, Tauber W. B. Posttraumatic endophthalmitis: the emerging role of Bacillus cereus infection. Rev Infect Dis. 1987 Jan-Feb;9(1):110–123. doi: 10.1093/clinids/9.1.110. [DOI] [PubMed] [Google Scholar]
  23. Davis J. L., Chan C. C., Nussenblatt R. B. Diagnostic vitrectomy in intermediate uveitis. Dev Ophthalmol. 1992;23:120–132. doi: 10.1159/000429640. [DOI] [PubMed] [Google Scholar]
  24. Davis J. L., Solomon D., Nussenblatt R. B., Palestine A. G., Chan C. C. Immunocytochemical staining of vitreous cells. Indications, techniques, and results. Ophthalmology. 1992 Feb;99(2):250–256. doi: 10.1016/s0161-6420(92)31984-0. [DOI] [PubMed] [Google Scholar]
  25. De Juan E., Green W. R., Rice T. A., Erozan Y. S. Optic disc neovascularization associated with ocular involvement in acute lymphocytic leukemia. Retina. 1982;2(2):61–64. doi: 10.1097/00006982-198200220-00001. [DOI] [PubMed] [Google Scholar]
  26. Dellon A. L., Stark W. J., Chretien P. B. Spontaneous resolution of endogenous Candida endophthalmitis complicating intravenous hyperalimentation. Am J Ophthalmol. 1975 Apr;79(4):648–654. doi: 10.1016/0002-9394(75)90805-3. [DOI] [PubMed] [Google Scholar]
  27. Deutsch D., Adler S., Teller J., Savir H. Endogenous candidal endophthalmitis. Ann Ophthalmol. 1989 Jul;21(7):260-5, 268. [PubMed] [Google Scholar]
  28. Doft B. H., Clarkson J. G., Rebell G., Forster R. K. Endogenous Aspergillus endophthalmitis in drug abusers. Arch Ophthalmol. 1980 May;98(5):859–862. doi: 10.1001/archopht.1980.01020030853010. [DOI] [PubMed] [Google Scholar]
  29. Donahue S. P., Greven C. M., Zuravleff J. J., Eller A. W., Nguyen M. H., Peacock J. E., Jr, Wagener M. W., Yu V. L. Intraocular candidiasis in patients with candidemia. Clinical implications derived from a prospective multicenter study. Ophthalmology. 1994 Jul;101(7):1302–1309. doi: 10.1016/s0161-6420(94)31175-4. [DOI] [PubMed] [Google Scholar]
  30. Donahue S. P., Kowalski R. P., Jewart B. H., Friberg T. R. Vitreous cultures in suspected endophthalmitis. Biopsy or vitrectomy? Ophthalmology. 1993 Apr;100(4):452–455. doi: 10.1016/s0161-6420(93)31623-4. [DOI] [PubMed] [Google Scholar]
  31. Eifrig D. E., Lockhart D. L., Berglund R. D., Knobloch W. H. Pars plana vitrectomy. Ophthalmic Surg. 1978 Oct;9(5):76–88. [PubMed] [Google Scholar]
  32. Eliott D., O'Brien T. P., Green W. R., Jampel H. D., Goldberg M. F. Elevated intraocular pressure, pigment dispersion and dark hypopyon in endogenous endophthalmitis from Listeria monocytogenes. Surv Ophthalmol. 1992 Sep-Oct;37(2):117–124. doi: 10.1016/0039-6257(92)90074-4. [DOI] [PubMed] [Google Scholar]
  33. Elkins B. S., Holland G. N., Opremcak E. M., Dunn J. P., Jr, Jabs D. A., Johnston W. H., Green W. R. Ocular toxoplasmosis misdiagnosed as cytomegalovirus retinopathy in immunocompromised patients. Ophthalmology. 1994 Mar;101(3):499–507. doi: 10.1016/s0161-6420(13)31267-6. [DOI] [PubMed] [Google Scholar]
  34. Engel H. M., Green W. R., Michels R. G., Rice T. A., Erozan Y. S. Diagnostic vitrectomy. Retina. 1981;1(2):121–149. doi: 10.1097/00006982-198101020-00009. [DOI] [PubMed] [Google Scholar]
  35. Engel H., de la Cruz Z. C., Jimenez-Abalahin L. D., Green W. R., Michels R. G. Cytopreparatory techniques for eye fluid specimens obtained by vitrectomy. Acta Cytol. 1982 Jul-Aug;26(4):551–560. [PubMed] [Google Scholar]
  36. Fagadau W. R., Maumenee A. E., Stark W. J., Jr, Datiles M. Posterior chamber intraocular lenses at the Wilmer Institute: a comparative analysis of complications and visual results. Br J Ophthalmol. 1984 Jan;68(1):13–18. doi: 10.1136/bjo.68.1.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Farrell P. L., Fan J. T., Smith R. E., Trousdale M. D. Donor cornea bacterial contamination. Cornea. 1991 Sep;10(5):381–386. doi: 10.1097/00003226-199109000-00004. [DOI] [PubMed] [Google Scholar]
  38. Feaster F. T., Nisbet R. M., Barber J. C. Aeromonas hydrophila corneal ulcer. Am J Ophthalmol. 1978 Jan;85(1):114–117. doi: 10.1016/s0002-9394(14)76675-9. [DOI] [PubMed] [Google Scholar]
  39. Feist R. M., Morris R. E., Witherspoon C. D., Blair N. P., Ticho B. H., White M. F., Jr Vitrectomy in asteroid hyalosis. Retina. 1990;10(3):173–177. [PubMed] [Google Scholar]
  40. Forster R. K., Abbott R. L., Gelender H. Management of infectious endophthalmitis. Ophthalmology. 1980 Apr;87(4):313–319. doi: 10.1016/s0161-6420(80)35241-x. [DOI] [PubMed] [Google Scholar]
  41. Forster R. K. Endophthalmitis. Diagnostic cultures and visual results. Arch Ophthalmol. 1974 Nov;92(5):387–392. doi: 10.1001/archopht.1974.01010010399005. [DOI] [PubMed] [Google Scholar]
  42. Forster R. K., Zachary I. G., Cottingham A. J., Jr, Norton E. W. Further observations on the diagnosis cause, and treatment of endophthalmitis. Am J Ophthalmol. 1976 Jan;81(1):52–56. doi: 10.1016/0002-9394(76)90190-2. [DOI] [PubMed] [Google Scholar]
  43. Freedman J., Gupta M., Bunke A. Endophthalmitis after trabeculectomy. Arch Ophthalmol. 1978 Jun;96(6):1017–1018. doi: 10.1001/archopht.1978.03910050541009. [DOI] [PubMed] [Google Scholar]
  44. Freeman L. N., Schachat A. P., Knox D. L., Michels R. G., Green W. R. Clinical features, laboratory investigations, and survival in ocular reticulum cell sarcoma. Ophthalmology. 1987 Dec;94(12):1631–1639. doi: 10.1016/s0161-6420(87)33256-7. [DOI] [PubMed] [Google Scholar]
  45. Freeman W. R., Schneiderman T. E. Invasive posterior segment diagnostic procedures in immunosuppressed patients. Int Ophthalmol Clin. 1989 Summer;29(2):119–126. doi: 10.1097/00004397-198902920-00010. [DOI] [PubMed] [Google Scholar]
  46. Frieling J. S., Rosenberg R., Edelstein M., Colby S. D., Kopelowitz N. N. Endogenous Aeromonas hydrophila endophthalmitis. Ann Ophthalmol. 1989 Mar;21(3):117–118. [PubMed] [Google Scholar]
  47. Funata M., Custis P., de la Cruz Z., de Juan E., Green W. R. Intraocular gnathostomiasis. Retina. 1993;13(3):240–244. doi: 10.1097/00006982-199313030-00010. [DOI] [PubMed] [Google Scholar]
  48. Gass J. D., Sever R. J., Grizzard W. S., Clarkson J. G., Blumenkranz M., Wind C. A., Shugarman R. Multifocal pigment epithelial detachments by reticulum cell sarcoma. A characteristic funduscopic picture. Retina. 1984 Summer-Fall;4(3):135–143. doi: 10.1097/00006982-198400430-00001. [DOI] [PubMed] [Google Scholar]
  49. Gass J. D., Trattler H. L. Retinal artery obstruction and atheromas associated with non-Hodgkin's large cell lymphoma (reticulum cell sarcoma). Arch Ophthalmol. 1991 Aug;109(8):1134–1139. doi: 10.1001/archopht.1991.01080080094039. [DOI] [PubMed] [Google Scholar]
  50. Getnick R. A., Rodrigues M. M. Endogenous fungal endophthalmitis in a drug addict. Am J Ophthalmol. 1974 May;77(5):680–683. doi: 10.1016/0002-9394(74)90531-5. [DOI] [PubMed] [Google Scholar]
  51. Goldey S. H., Stern G. A., Oblon D. J., Mendenhall N. P., Smith L. J., Duque R. E. Immunophenotypic characterization of an unusual T-cell lymphoma presenting as anterior uveitis. A clinicopathologic case report. Arch Ophthalmol. 1989 Sep;107(9):1349–1353. doi: 10.1001/archopht.1989.01070020419047. [DOI] [PubMed] [Google Scholar]
  52. Green W. R. Diagnostic cytopathology of ocular fluid specimens. Ophthalmology. 1984 Jun;91(6):726–749. doi: 10.1016/s0161-6420(84)34253-1. [DOI] [PubMed] [Google Scholar]
  53. Greenwald M. J., Wohl L. G., Sell C. H. Metastatic bacterial endophthalmitis: a contemporary reappraisal. Surv Ophthalmol. 1986 Sep-Oct;31(2):81–101. doi: 10.1016/0039-6257(86)90076-7. [DOI] [PubMed] [Google Scholar]
  54. Gressel M. G., Parrish R. K., 2nd, Folberg R. 5-fluorouracil and glaucoma filtering surgery: I. An animal model. Ophthalmology. 1984 Apr;91(4):378–383. doi: 10.1016/s0161-6420(84)34277-4. [DOI] [PubMed] [Google Scholar]
  55. Grossniklaus H. E., Frank K. E., Farhi D. C., Jacobs G., Green W. R. Hemoglobin spherulosis in the vitreous cavity. Arch Ophthalmol. 1988 Jul;106(7):961–962. doi: 10.1001/archopht.1988.01060140107035. [DOI] [PubMed] [Google Scholar]
  56. Guss R. B., Koenig S., De La Pena W., Marx M., Kaufman H. E. Endophthalmitis after penetrating keratoplasty. Am J Ophthalmol. 1983 May;95(5):651–658. doi: 10.1016/0002-9394(83)90385-9. [DOI] [PubMed] [Google Scholar]
  57. Hattenhauer J. M., Lipsich M. P. Late endophthalmitis after filtering surgery. Am J Ophthalmol. 1971 Dec;72(6):1097–1101. doi: 10.1016/0002-9394(71)91215-3. [DOI] [PubMed] [Google Scholar]
  58. Heaven C. J., Mann P. J., Boase D. L. Endophthalmitis following extracapsular cataract surgery: a review of 32 cases. Br J Ophthalmol. 1992 Jul;76(7):419–423. doi: 10.1136/bjo.76.7.419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Heher K. L., Lim J. I., Haller J. A., Jampel H. D. Late-onset sterile endophthalmitis after Molteno tube implantation. Am J Ophthalmol. 1992 Dec 15;114(6):771–772. doi: 10.1016/s0002-9394(14)74062-0. [DOI] [PubMed] [Google Scholar]
  60. Heinemann M. H., Gold J. M., Maisel J. Bilateral toxoplasma retinochoroiditis in a patient with acquired immune deficiency syndrome. Retina. 1986 Winter;6(4):224–227. doi: 10.1097/00006982-198606040-00006. [DOI] [PubMed] [Google Scholar]
  61. Ho P. C., McMeel J. W. Bacterial endophthalmitis after retinal surgery. Retina. 1983;3(2):99–102. doi: 10.1097/00006982-198300320-00005. [DOI] [PubMed] [Google Scholar]
  62. Huang J. S., Russack V., Flores-Aguilar M., Gharib M., Freeman W. R. Evaluation of cytologic specimens obtained during experimental vitreous biopsy. Retina. 1993;13(2):160–165. doi: 10.1097/00006982-199313020-00014. [DOI] [PubMed] [Google Scholar]
  63. Javitt J. C., Street D. A., Tielsch J. M., Wang Q., Kolb M. M., Schien O., Sommer A., Bergner M., Steinberg E. P. National outcomes of cataract extraction. Retinal detachment and endophthalmitis after outpatient cataract surgery. Cataract Patient Outcomes Research Team. Ophthalmology. 1994 Jan;101(1):100–106. doi: 10.1016/s0161-6420(13)31251-2. [DOI] [PubMed] [Google Scholar]
  64. Javitt J. C., Vitale S., Canner J. K., Street D. A., Krakauer H., McBean A. M., Sommer A. National outcomes of cataract extraction. Endophthalmitis following inpatient surgery. Arch Ophthalmol. 1991 Aug;109(8):1085–1089. doi: 10.1001/archopht.1991.01080080045025. [DOI] [PubMed] [Google Scholar]
  65. Joos K. M., Bueche M. J., Palmberg P. F., Feuer W. J., Grajewski A. L. One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. Ophthalmology. 1995 Jan;102(1):76–83. doi: 10.1016/s0161-6420(95)31050-0. [DOI] [PubMed] [Google Scholar]
  66. Kattan H. M., Flynn H. W., Jr, Pflugfelder S. C., Robertson C., Forster R. K. Nosocomial endophthalmitis survey. Current incidence of infection after intraocular surgery. Ophthalmology. 1991 Feb;98(2):227–238. [PubMed] [Google Scholar]
  67. Katz L. J., Cantor L. B., Spaeth G. L. Complications of surgery in glaucoma. Early and late bacterial endophthalmitis following glaucoma filtering surgery. Ophthalmology. 1985 Jul;92(7):959–963. doi: 10.1016/s0161-6420(85)33948-9. [DOI] [PubMed] [Google Scholar]
  68. Khurana A. K., Mathur S. K., Ahluwalia B. K., Jain K., Sood S. An unusual case of endogenous aspergillus endophthalmitis. Acta Ophthalmol (Copenh) 1989 Jun;67(3):315–318. doi: 10.1111/j.1755-3768.1989.tb01878.x. [DOI] [PubMed] [Google Scholar]
  69. Koul S., Philipson A., Arvidson S. Role of aqueous and vitreous cultures in diagnosing infectious endophthalmitis in rabbits. Acta Ophthalmol (Copenh) 1990 Aug;68(4):466–469. doi: 10.1111/j.1755-3768.1990.tb01677.x. [DOI] [PubMed] [Google Scholar]
  70. Koul S., Philipson A., Philipson B. T. Incidence of endophthalmitis in Sweden. Acta Ophthalmol (Copenh) 1989 Oct;67(5):499–503. doi: 10.1111/j.1755-3768.1989.tb04099.x. [DOI] [PubMed] [Google Scholar]
  71. Laatikainen L., Tarkkanen A., Koivuniemi A. Vitrectomy. Clinical data and cytologic findings of vitrectomy specimens. Int Ophthalmol. 1985 Mar;7(3-4):215–222. doi: 10.1007/BF00128368. [DOI] [PubMed] [Google Scholar]
  72. Lamping K. A., Belkin J. K. 5-Fluorouracil and mitomycin C in pseudophakic patients. Ophthalmology. 1995 Jan;102(1):70–75. doi: 10.1016/s0161-6420(95)31051-2. [DOI] [PubMed] [Google Scholar]
  73. Lance S. E., Friberg T. R., Kowalski R. P. Aspergillus flavus endophthalmitis and retinitis in an intravenous drug abuser. A therapeutic success. Ophthalmology. 1988 Jul;95(7):947–949. doi: 10.1016/s0161-6420(88)33087-3. [DOI] [PubMed] [Google Scholar]
  74. Lang G. K., Green W. R. Clinicopathologic studies of keratoplasty eyes obtained surgically. Cornea. 1985;4(4):229–238. [PubMed] [Google Scholar]
  75. Leveille A. S., McMullan F. D., Cavanagh H. D. Endophthalmitis following penetrating keratoplasty. Ophthalmology. 1983 Jan;90(1):38–39. doi: 10.1016/s0161-6420(83)34601-7. [DOI] [PubMed] [Google Scholar]
  76. Maguire A. M., Green W. R., Michels R. G., Erozan Y. S. Recovery of intraocular Toxocara canis by pars plana vitrectomy. Ophthalmology. 1990 May;97(5):675–680. doi: 10.1016/s0161-6420(90)32528-9. [DOI] [PubMed] [Google Scholar]
  77. Majerovics A., Tanenbaum H. L. Endophthalmitis and pars plana vitrectomy. Can J Ophthalmol. 1984 Feb;19(1):25–28. [PubMed] [Google Scholar]
  78. Mandelbaum S., Forster R. K., Gelender H., Culbertson W. Late onset endophthalmitis associated with filtering blebs. Ophthalmology. 1985 Jul;92(7):964–972. doi: 10.1016/s0161-6420(85)33947-7. [DOI] [PubMed] [Google Scholar]
  79. Mao L. K., Flynn H. W., Jr, Miller D., Pflugfelder S. C. Endophthalmitis caused by streptococcal species. Arch Ophthalmol. 1992 Jun;110(6):798–801. doi: 10.1001/archopht.1992.01080180070030. [DOI] [PubMed] [Google Scholar]
  80. Marak G. E., Jr Phacoanaphylactic endophthalmitis. Surv Ophthalmol. 1992 Mar-Apr;36(5):325–339. doi: 10.1016/0039-6257(92)90109-7. [DOI] [PubMed] [Google Scholar]
  81. Martin D. F., Chan C. C., de Smet M. D., Palestine A. G., Davis J. L., Whitcup S. M., Burnier M. N., Jr, Nussenblatt R. B. The role of chorioretinal biopsy in the management of posterior uveitis. Ophthalmology. 1993 May;100(5):705–714. doi: 10.1016/s0161-6420(93)31585-x. [DOI] [PubMed] [Google Scholar]
  82. McClellan K., Coster D. J., Badenoch P. R., Sanders R., Chandraratnam E., Kupa A. Endophthalmitis following cataract extraction. Aust N Z J Ophthalmol. 1987 Feb;15(1):19–23. doi: 10.1111/j.1442-9071.1987.tb00301.x. [DOI] [PubMed] [Google Scholar]
  83. McDonnell P. J., McDonnell J. M., Brown R. H., Green W. R. Ocular involvement in patients with fungal infections. Ophthalmology. 1985 May;92(5):706–709. doi: 10.1016/s0161-6420(85)33989-1. [DOI] [PubMed] [Google Scholar]
  84. Menikoff J. A., Speaker M. G., Marmor M., Raskin E. M. A case-control study of risk factors for postoperative endophthalmitis. Ophthalmology. 1991 Dec;98(12):1761–1768. doi: 10.1016/s0161-6420(91)32053-0. [DOI] [PubMed] [Google Scholar]
  85. Merenmies L., Tarkkanen A. Causes of enucleation following cataract surgery. Acta Ophthalmol (Copenh) 1977 Jun;55(3):347–352. doi: 10.1111/j.1755-3768.1977.tb06108.x. [DOI] [PubMed] [Google Scholar]
  86. Michels R. G., Machemer R., Mueller-Jensen K. Vitreous surgery: history and current concepts. Ophthalmic Surg. 1974 Winter;5(4):13–59. [PubMed] [Google Scholar]
  87. Michelson J. B., Michelson P. E., Bordin G. M., Chisari F. V. Ocular reticulum cell sarcoma. Presentation as retinal detachment with demonstration of monoclonal immunoglobulin light chains on the vitreous cells. Arch Ophthalmol. 1981 Aug;99(8):1409–1411. doi: 10.1001/archopht.1981.03930020283017. [DOI] [PubMed] [Google Scholar]
  88. Minckler D. S., Font R. L., Zimmerman L. E. Uveitis and reticulum cell sarcoma of brain with bilateral neoplastic seeding of vitreous without retinal or uveal involvement. Am J Ophthalmol. 1975 Sep;80(3 Pt 1):433–439. doi: 10.1016/0002-9394(75)90531-0. [DOI] [PubMed] [Google Scholar]
  89. Miño de Kaspar H., Kollmann M., Klauss V. Endophthalmitis. Bedeutung mikrobiologischer Untersuchungen für Therapie und Prognose. Ophthalmologe. 1993 Dec;90(6):726–736. [PubMed] [Google Scholar]
  90. Molinari H., Polack F. M. A retrospective study of endophthalmitis. Metab Pediatr Syst Ophthalmol. 1982;6(3-4):221–225. [PubMed] [Google Scholar]
  91. Mégevand G. S., Salmon J. F., Scholtz R. P., Murray A. D. The effect of reducing the exposure time of mitomycin C in glaucoma filtering surgery. Ophthalmology. 1995 Jan;102(1):84–90. doi: 10.1016/s0161-6420(95)31049-4. [DOI] [PubMed] [Google Scholar]
  92. Naidoff M. A., Green W. R. Endogenous Aspergillus endophthalmitis occurring after kidney transplant. Am J Ophthalmol. 1975 Mar;79(3):502–509. doi: 10.1016/0002-9394(75)90628-5. [DOI] [PubMed] [Google Scholar]
  93. Naumann G. O., Rummelt V. Block excision of cystic and diffuse epithelial ingrowth of the anterior chamber. Report on 32 consecutive patients. Arch Ophthalmol. 1992 Feb;110(2):223–227. doi: 10.1001/archopht.1992.01080140079031. [DOI] [PubMed] [Google Scholar]
  94. Nirankari V. S., Karesh J. W., Lakhanpal V., Schocket S. S. Pseudophakic endophthalmitis. Ophthalmic Surg. 1983 Apr;14(4):314–316. [PubMed] [Google Scholar]
  95. Nölle B., Eckardt C. Vitrectomy in multifocal chorioretinitis. Ger J Ophthalmol. 1993 Feb;2(1):14–19. [PubMed] [Google Scholar]
  96. Okada A. A., Johnson R. P., Liles W. C., D'Amico D. J., Baker A. S. Endogenous bacterial endophthalmitis. Report of a ten-year retrospective study. Ophthalmology. 1994 May;101(5):832–838. [PubMed] [Google Scholar]
  97. Olk R. J., Bohigian G. M. The management of endophthalmitis: diagnostic and therapeutic guidelines including the use of vitrectomy. Ophthalmic Surg. 1987 Apr;18(4):262–267. [PubMed] [Google Scholar]
  98. Ormerod L. D., Becker L. E., Cruise R. J., Grohar H. I., Paton B. G., Frederick A. R., Jr, Topping T. M., Weiter J. J., Buzney S. M., Baker A. S. Endophthalmitis caused by the coagulase-negative staphylococci. 2. Factors influencing presentation after cataract surgery. Ophthalmology. 1993 May;100(5):724–729. doi: 10.1016/s0161-6420(93)31583-6. [DOI] [PubMed] [Google Scholar]
  99. Ormerod L. D., Ho D. D., Becker L. E., Cruise R. J., Grohar H. I., Paton B. G., Frederick A. R., Jr, Topping T. M., Weiter J. J., Buzney S. M. Endophthalmitis caused by the coagulase-negative staphylococci. 1. Disease spectrum and outcome. Ophthalmology. 1993 May;100(5):715–723. doi: 10.1016/s0161-6420(93)31584-8. [DOI] [PubMed] [Google Scholar]
  100. Parke D. W., 2nd, Jones D. B., Gentry L. O. Endogenous endophthalmitis among patients with candidemia. Ophthalmology. 1982 Jul;89(7):789–796. doi: 10.1016/s0161-6420(82)34722-3. [DOI] [PubMed] [Google Scholar]
  101. Perina B., Kurz G. H., Mittl R. N. Unsuspected fungal endophthalmitis diagnosed in vitrectomy specimen. Br J Ophthalmol. 1976 Sep;60(9):614–617. doi: 10.1136/bjo.60.9.614. [DOI] [PMC free article] [PubMed] [Google Scholar]
  102. Perkins T. W., Cardakli U. F., Eisele J. R., Kaufman P. L., Heatley G. A. Adjunctive mitomycin C in Molteno implant surgery. Ophthalmology. 1995 Jan;102(1):91–97. doi: 10.1016/s0161-6420(95)31048-2. [DOI] [PubMed] [Google Scholar]
  103. Peterson K., Gordon K. B., Heinemann M. H., DeAngelis L. M. The clinical spectrum of ocular lymphoma. Cancer. 1993 Aug 1;72(3):843–849. doi: 10.1002/1097-0142(19930801)72:3<843::aid-cncr2820720333>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  104. Pfeifer J. D., Grand M. G., Thomas M. A., Berger A. R., Lucarelli M. J., Smith M. E. Endogenous Pseudallescheria boydii endophthalmitis. Clinicopathologic findings in two cases. Arch Ophthalmol. 1991 Dec;109(12):1714–1717. doi: 10.1001/archopht.1991.01080120098035. [DOI] [PubMed] [Google Scholar]
  105. Phillips W. B., 2nd, Wong T. P., Bergren R. L., Friedberg M. A., Benson W. E. Late onset endophthalmitis associated with filtering blebs. Ophthalmic Surg. 1994 Feb;25(2):88–91. [PubMed] [Google Scholar]
  106. Piro P., Pappas H. R., Erozan Y. S., Michels R. G., Sherman S. H., Green W. R. Diagnostic vitrectomy in metastatic breast carcinoma in the vitreous. Retina. 1982;2(3):182–188. doi: 10.1097/00006982-198200230-00010. [DOI] [PubMed] [Google Scholar]
  107. Polack F. M. Ocular infections after keratoplasty. Cornea. 1984;3(1):3–4. [PubMed] [Google Scholar]
  108. Powe N. R., Schein O. D., Gieser S. C., Tielsch J. M., Luthra R., Javitt J., Steinberg E. P. Synthesis of the literature on visual acuity and complications following cataract extraction with intraocular lens implantation. Cataract Patient Outcome Research Team. Arch Ophthalmol. 1994 Feb;112(2):239–252. doi: 10.1001/archopht.1994.01090140115033. [DOI] [PubMed] [Google Scholar]
  109. Priem H., Verbraeken H., de Laey J. J. Diagnostic problems in chronic vitreous inflammation. Graefes Arch Clin Exp Ophthalmol. 1993 Aug;231(8):453–456. doi: 10.1007/BF02044231. [DOI] [PubMed] [Google Scholar]
  110. Rao N. A. A laboratory approach to rapid diagnosis of ocular infections and prospects for the future. Am J Ophthalmol. 1989 Mar 15;107(3):283–291. doi: 10.1016/0002-9394(89)90314-0. [DOI] [PubMed] [Google Scholar]
  111. Richardson J., Wood C. M., Mackay L. J., Gardner E. S. A vitreoretinal service. BMJ. 1989 Jul 22;299(6693):241–245. doi: 10.1136/bmj.299.6693.241. [DOI] [PMC free article] [PubMed] [Google Scholar]
  112. Rutzen A. R., Ortega-Larrocea G., Dugel P. U., Chong L. P., Lopez P. F., Rao N. A. Retinal and choroidal biopsy in intraocular inflammation: a clinicopathologi study. Trans Am Ophthalmol Soc. 1994;92:431–458. [PMC free article] [PubMed] [Google Scholar]
  113. Samples J. R., Van Buskirk E. M. Epithelial ingrowth on an intraocular lens. Ophthalmic Surg. 1984 Oct;15(10):869–870. [PubMed] [Google Scholar]
  114. Sawusch M. R., Michels R. G., Stark W. J., Bruner W. E., Annable W. L., Green W. R. Endophthalmitis due to Propionibacterium acnes sequestered between IOL optic and posterior capsule. Ophthalmic Surg. 1989 Feb;20(2):90–92. [PubMed] [Google Scholar]
  115. Schemmer G. B., Driebe W. T., Jr Posttraumatic Bacillus cereus endophthalmitis. Arch Ophthalmol. 1987 Mar;105(3):342–344. doi: 10.1001/archopht.1987.01060030062026. [DOI] [PubMed] [Google Scholar]
  116. Schwartz M. F., Green W. R., Michels R. G., Kincaid M. C., Fogle J. An unusual case of ocular involvement in primary systemic nonfamilial amyloidosis. Ophthalmology. 1982 Apr;89(4):394–401. doi: 10.1016/s0161-6420(82)34780-6. [DOI] [PubMed] [Google Scholar]
  117. Selsky E. J., Knox D. L., Maumenee A. E., Green W. R. Ocular involvement in Whipple's disease. Retina. 1984 Spring-Summer;4(2):103–106. doi: 10.1097/00006982-198400420-00006. [DOI] [PubMed] [Google Scholar]
  118. Sidoti P. A., Minckler D. S., Baerveldt G., Lee P. P., Heuer D. K. Epithelial ingrowth and glaucoma drainage implants. Ophthalmology. 1994 May;101(5):872–875. doi: 10.1016/s0161-6420(94)31245-0. [DOI] [PubMed] [Google Scholar]
  119. Snip R. C., Michels R. G. Pars plana vitrectomy in the management of endogenous Candida endophthalmitis. Am J Ophthalmol. 1976 Nov;82(5):699–704. doi: 10.1016/0002-9394(76)90005-2. [DOI] [PubMed] [Google Scholar]
  120. Sorrell T. C., Dunlop C., Collignon P. J., Harding J. A. Exogenous ocular candidiasis associated with intravenous heroin abuse. Br J Ophthalmol. 1984 Nov;68(11):841–845. doi: 10.1136/bjo.68.11.841. [DOI] [PMC free article] [PubMed] [Google Scholar]
  121. Speaker M. G., Milch F. A., Shah M. K., Eisner W., Kreiswirth B. N. Role of external bacterial flora in the pathogenesis of acute postoperative endophthalmitis. Ophthalmology. 1991 May;98(5):639–650. doi: 10.1016/s0161-6420(91)32239-5. [DOI] [PubMed] [Google Scholar]
  122. Stark W. J., Fagadau W., Lindsey P. S., Taylor H. R., Michels R. G. Management of persistent hyperplastic primary vitreous. Aust J Ophthalmol. 1983 Aug;11(3):195–200. doi: 10.1111/j.1442-9071.1983.tb01078.x. [DOI] [PubMed] [Google Scholar]
  123. Stark W. J. Management of epithelial ingrowth and cysts. Dev Ophthalmol. 1981;5:64–73. doi: 10.1159/000400942. [DOI] [PubMed] [Google Scholar]
  124. States B., Segal S. Levels of gamma-glutamyltranspeptidase in cultured skin fibroblasts from cystinotics and normals. Life Sci. 1980 Nov 24;27(21):1985–1990. doi: 10.1016/0024-3205(80)90419-1. [DOI] [PubMed] [Google Scholar]
  125. Stone S. P., Bendig J., Hakim J., Kinnear P. E., Azadian B. S., Clifford-Rose F. Cryptococcal meningitis presenting as uveitis. Br J Ophthalmol. 1988 Mar;72(3):167–170. doi: 10.1136/bjo.72.3.167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  126. Tabbara K. F. Late infections following filtering procedures. Ann Ophthalmol. 1976 Oct;8(10):1228–1231. [PubMed] [Google Scholar]
  127. Valluri S., Moorthy R. S., Liggett P. E., Rao N. A. Endogenous Aspergillus endophthalmitis in an immunocompetent individual. Int Ophthalmol. 1993 Jun;17(3):131–135. doi: 10.1007/BF00942926. [DOI] [PubMed] [Google Scholar]
  128. Verweij P. E., Rademakers A. J., Koopmans P. P., Meis J. F. Endophthalmitis as presenting symptom of group G streptococcal endocarditis. Infection. 1994 Jan-Feb;22(1):56–57. doi: 10.1007/BF01780770. [DOI] [PubMed] [Google Scholar]
  129. Washington J. A., 2nd Aeromonas hydrophila in clinical bacteriologic specimens. Ann Intern Med. 1972 Apr;76(4):611–614. doi: 10.7326/0003-4819-76-4-611. [DOI] [PubMed] [Google Scholar]
  130. Wheeler D. T., Stager D. R., Weakley D. R., Jr Endophthalmitis following pediatric intraocular surgery for congenital cataracts and congenital glaucoma. J Pediatr Ophthalmol Strabismus. 1992 May-Jun;29(3):139–141. doi: 10.3928/0191-3913-19920501-04. [DOI] [PubMed] [Google Scholar]
  131. Whitcup S. M., de Smet M. D., Rubin B. I., Palestine A. G., Martin D. F., Burnier M., Jr, Chan C. C., Nussenblatt R. B. Intraocular lymphoma. Clinical and histopathologic diagnosis. Ophthalmology. 1993 Sep;100(9):1399–1406. doi: 10.1016/s0161-6420(93)31469-7. [DOI] [PubMed] [Google Scholar]
  132. Willman C. L., Griffith B. B., Whittaker M. Molecular genetic approaches for the diagnosis of clonality in lymphoid neoplasms. Clin Lab Med. 1990 Mar;10(1):119–149. [PubMed] [Google Scholar]
  133. Wolner B., Liebmann J. M., Sassani J. W., Ritch R., Speaker M., Marmor M. Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. Ophthalmology. 1991 Jul;98(7):1053–1060. doi: 10.1016/s0161-6420(91)32177-8. [DOI] [PubMed] [Google Scholar]
  134. Yen M. Y., Liu J. H. Malignant lymphoma involving the optic nerve head and the retina. Ann Ophthalmol. 1985 Nov;17(11):697–700. [PubMed] [Google Scholar]
  135. de Smet M. D., Nussenblatt R. B., Davis J. L., Palestine A. G. Large cell lymphoma masquerading as a viral retinitis. Int Ophthalmol. 1990 Oct;14(5-6):413–417. doi: 10.1007/BF00163568. [DOI] [PubMed] [Google Scholar]
  136. ten Doesschate M. J. Lens-induced inflammation. Int Ophthalmol. 1985 Mar;7(3-4):193–201. doi: 10.1007/BF00128366. [DOI] [PubMed] [Google Scholar]

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