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. 2025 Aug 30;80(4):819–832. doi: 10.32592/ARI.2025.80.4.819

Table 2.

Applications of Artificial Intelligence and Machine Learning in Animal Biotechnology.

Description Citation
Applications of machine learning in livestock management
Analyzing Internal and External Factors in Livestock Supply Forecasting: This study uses machine learning algorithms to predict future livestock values, focusing on sustainability in the pork market. ( 1 )
Predictive Models for Livestock Output: This research applies machine learning techniques to predict livestock outputs, utilizing various predictors such as livestock units and costs to improve forecasting. ( 2 )
Predicting the Weight of Livestock: A machine learning model that utilizes algorithms like Random Forest and Ridge Regression to predict livestock weight based on different input features. ( 5 )
Applications of machine learning in the field of animal genetics
Identification of Potential Feature Genes for Drug Efficacy in Non-Alcoholic Steatohepatitis Animal Model: This study uses machine learning algorithms to identify key genes that predict treatment responses, focusing on genetic and epigenetic RNA markers in an animal model. ( 7 )
Genomic Prediction of Cow Behavioral Traits Using Machine Learning: This research focuses on predicting behavioral traits in Holstein cattle, using data from automated milking systems and machine learning models to enhance genetic selection. ( 9 )
Genomic Prediction in Chickens Using Bioinformatics and Machine Learning: Integrating bioinformatics and machine learning, this research aims to predict genetic pathways in chickens, identifying crucial genes related to growth and other traits. ( 11 )
Recent advances in animal cloning coupled with machine learning
Serine Protease Inhibitor Identification Using Machine Learning: This research utilized machine learning strategies to identify and analyze serine protease inhibitors, key proteins that play a role in cloning experiments in the animal's physiological context. ( 13 )
In-Silico Cloning for Vaccine Constructs against Bovine Coronavirus: This study applied machine learning for immunogenic epitope mapping and in-silico cloning to expedite the creation of vaccine constructs, focusing on expression vectors for animal applications. ( 15 )
Mapping Protective Precision Vaccines using Machine Learning: Researchers applied machine learning to structural proteomics and in-silico cloning to develop precision vaccines for Mycoplasma pulmonis, optimizing the vaccine before animal testing. ( 17 )
The integration of AI & ML in embryo transfer technologies
Time-lapse Imaging to Differentiate Embryos: This study uses machine learning algorithms to analyze time-lapse imaging and differentiate embryos from young and old mice for more efficient embryo transfer, with or without preimplantation genetic testing. ( 19 )
Spectroscopy and Machine Learning for Bovine Embryo Grading: The research focuses on integrating imaging, spectroscopy, and machine learning models to automatically predict embryo quality, aiming to improve pregnancy success rates in bovine embryo transfer. ( 21 )
AI-Assisted Embryo Selection in Newts: This study developed an AI-assisted system for selecting viable embryos in Iberian ribbed newts, which is used for fetal development toxicity testing in embryo transfer technologies. ( 23 )
Selective Breeding and AI
Machine Learning for Genomic Selection in Pacific White Shrimp: This study evaluates machine learning methods for genomic selection, focusing on growth traits in Pacific white shrimp, enhancing selective breeding programs. ( 25 )
Machine Learning and Survival Traits in Olive Flounder: This study compares machine learning models with traditional methods for genomic selection related to viral resistance traits in olive flounder, enhancing survival traits. ( 27 )
Bioinformatics in Animal Breeding: A review discussing the integration of bioinformatics and machine learning in animal breeding and genetics to enhance the accuracy of selective breeding programs. ( 29 )
Machine Learning Techniques for Enhancing Accuracy of prediction
Prediction of Growth and Feed Efficiency in Mink: This study applies machine learning algorithms to predict growth and feed efficiency traits in mink, enhancing the accuracy of predictions for selective breeding programs. ( 31 )
Genomic Prediction of Cow Behavioral Traits: Machine learning methods, including CNN and MLP, are used to predict cow behavioral traits in Holstein cattle, achieving moderate accuracies, with CNN showing the highest accuracy. ( 9 )
Animal Healthcare and Diagnostic Accuracy: A review on the role of machine learning in animal healthcare, emphasizing its ability to improve diagnostic accuracy in various animal health-related applications. ( 34 )
Aquaculture and AI
ANN Algorithm
Random Forest: Used to identify aquaculture ponds and optimize aquaculture area management ( 36 )
Deep Learning: Image dataset for fish disease detection to ensure aquaculture health ( 38 )
Decision Trees: AI-based fish growth prediction and optimization of water quality ( 40 )
Artificial Intelligence and Machine Learning in forest animals
Study examining vertical foraging niches in mammals and birds using functional traits and phylogenetic data to understand ecological and evolutionary patterns. ( 41 )
Deep learning-based model called Deep Indel for predicting outcomes of CRISPR/Cas9 genome editing with improved accuracy and interpretability. ( 43 )
Research on the local adaptation of Aedesaegypti mosquitoes, highlighting genomic variations linked to environmental conditions. ( 45 )
Investigation of microbial compositions in ticks from neotropical forest fragments, analyzing intrinsic and extrinsic factors influencing microbiome structure. ( 46 )