Table 2.
Hazard ratios (95% CI) of dysglycemia, diabetes, and prediabetes stratified by ByG index
| Exposure | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| (HR, 95% CI) | P-value | (HR, 95% CI) | P-value | (HR, 95% CI) | P-value | |
| Dysglycemia | ||||||
| Per SD increment | 1.57 (1.36, 1.80) | < 0.001 | 1.61 (1.40, 1.85) | < 0.001 | 1.56 (1.34, 1.80) | < 0.001 |
| ByG Tertiles | ||||||
| T1 | Reference | Reference | Reference | |||
| T2 | 1.70 (1.10, 2.62) | 0.017 | 1.69 (1.09, 2.61) | 0.018 | 1.60 (1.03, 2.49) | 0.037 |
| T3 | 3.32 (2.24, 4.91) | < 0.001 | 3.49 (2.35, 5.18) | < 0.001 | 3.20 (2.13, 4.80) | < 0.001 |
| P for trend | < 0.001 | < 0.001 | < 0.001 | |||
| Diabetes | ||||||
| Per SD increment | 1.65 (1.40, 1.94) | < 0.001 | 1.68 (1.42, 1.97) | < 0.001 | 1.64 (1.38, 1.95) | < 0.001 |
| ByG Tertiles | ||||||
| T1 | Reference | Reference | Reference | |||
| T2 | 2.16 (1.31, 3.57) | 0.003 | 2.19 (1.32, 3.61) | 0.002 | 2.05 (1.20, 3.48) | 0.008 |
| T3 | 3.70 (2.31, 5.91) | < 0.001 | 3.77 (2.35, 6.05) | < 0.001 | 3.38 (2.02, 5.66) | < 0.001 |
| P for trend | < 0.001 | < 0.001 | < 0.001 | |||
| Prediabetes | ||||||
| Per SD increment | 1.35 (1.02, 1.79) | 0.035 | 1.44 (1.10, 1.89) | 0.009 | 1.39 (1.04, 1.84) | 0.024 |
| ByG Tertiles | ||||||
| T1 | Reference | Reference | Reference | |||
| T2 | 1.08 (0.48, 2.46) | 0.852 | 1.13 (0.49, 2.56) | 0.778 | 1.11 (0.48, 2.59) | 0.801 |
| T3 | 2.66 (1.33, 5.34) | 0.006 | 3.06 (1.51, 6.20) | 0.002 | 2.95 (1.44, 6.06) | 0.003 |
| P for trend | 0.003 | < 0.001 | 0.002 | |||
Model 1: adjusted for age, sex and ethnicity. Model 2: adjusted for variables in model 1 plus drinking status, baseline CHD, baseline stroke, smoking status, DBP, and SBP. Model 3: adjusted for variables in model 2 plus ALT, eGFR, TG, HDL-C, ACEIs/ARBs, β-blockers, CCBs, diuretics, statins, AHI, nadir SaO2, mean SaO2, and regular CPAP treatment
HR, hazard ratio; CI, confidence interval. Other abbreviations appear in Table 2