Table 3.
Fold change of repressed gene expression in B lymphoblasts treated with ionophore A23187. Genes listed here showed a decreased gene expression (2-fold or more) in at least one of the three B lymphoblasts cultured for 48 h with 200 nM A23187. Data are fold changes calculated from hybridization values in treated versus non treated cells for each one of the B lymphoblasts respectively (see fold-changes < 0.5 in additional file 1 corresponding to <-1/0.5 in this table). For each functional group, the genes were ordered by using a program for gene clustering. *Fourteen genes are basally under-expressed in Scott B lymphoblasts compared to control cells.
| Accession no. | control | daughter's | Scott | Gene definition |
| Histones | ||||
| X57129 | -3.79 | -3.59 | -6.54 | H1.2* |
| X00088 | -6.80 | -3.41 | -3.62 | H2b/r* |
| Z80779 | -4.49 | -2.11 | -2.31 | H2B/g* |
| Z80782 | -2.96 | -2.42 | -3.41 | H2B/k* |
| Z83336 | -2.98 | -2.12 | -2.08 | H2B/d* |
| L19779 | -2.97 | -2.01 | -1.66 | H2A.2* |
| AJ223352 | -2.57 | -1.71 | -2.57 | H2B/a* |
| Z83740 | -2.92 | -1.69 | -1.83 | H2B/c* |
| U91328 | -2.81 | -1.31 | -1.65 | H2A-like protein* |
| AJ223353 | -3.12 | -1.92 | -1.27 | H2B/b |
| Z83738 | -3.08 | -1.88 | -1.98 | H2B/e* |
| Z80780 | -3.06 | -1.84 | -2.85 | H2B/h* |
| X14850 | -1.45 | -1.40 | -3.20 | H2A.X |
| Cell cycle and proliferation | ||||
| AF041248 | -2.58 | -1.78 | -1.84 | CDKN2C* |
| X04757 | -2.53 | -2.55 | -1.31 | alpha-tubulin |
| J00139 | -2.35 | -2.35 | -5.23 | dihydrofolate reductase |
| U05340 | -3.12 | -2.44 | -6.60 | p55CDC |
| U37426 | -2.07 | -1.41 | -5.10 | HKSP |
| AF067656 | -2.18 | -1.26 | -4.08 | ZW10 interactor |
| AF011468 | -2.20 | -1.97 | -6.05 | BTAK |
| M25753 | -2.13 | -1.91 | -7.30 | cyclin B |
| Z36714 | -2.20 | -1.94 | -3.74 | cyclin F |
| D55716 | -2.04 | -1.57 | -3.25 | P1cdc47 |
| D14678 | -1.92 | -2.05 | -3.63 | kinesin-related protein |
| X76771 | -1.85 | -1.17 | -2.75 | flap endonuclease-1 |
| X62534 | -1.38 | -1.15 | -3.20 | HMG-2 |
| X54942 | -1.43 | -1.48 | -2.79 | ckshs2 |
| L37747 | -1.65 | -1.63 | -2.84 | lamin B1 |
| L25876 | -1.91 | -1.69 | -3.63 | CIP2 |
| D14657 | -1.82 | -1.27 | -3.35 | mRNA for KIAA0101 (p15-PAF) |
| L16991 | -1.92 | -1.78 | -4.08 | CDC8 |
| AB024704 | -1.76 | -1.86 | -4.60 | fls353 |
| X13293 | -1.93 | -1.69 | -5.74 | B-myb* |
| X05360 | -1.84 | -1.04 | -4.12 | CDC2 |
| X51688 | -1.62 | 1.05 | -5.23 | cyclin A |
| U63743 | -2.00 | -1.96 | -6.59 | centromere-associated kinesin |
| AF017790 | -1.85 | -1.55 | -4.40 | retinoblastoma-associated protein |
| AF004022 | -1.92 | -1.62 | -5.11 | protein kinase STK12 |
| U14518 | -2.00 | -1.65 | -5.02 | CENP-A |
| U30872 | -1.68 | -1.49 | -5.00 | mitosin |
| J04088 | -1.70 | -1.22 | -5.16 | top2 |
| AF035933 | -1.80 | -1.21 | -4.54 | protein kinase SSK1 |
| K02581 | -1.91 | -1.63 | -5.02 | thymidine kinase* |
| U73379 | -1.79 | -1.66 | -8.96 | cyclin-selective ubiquitin carrier |
| Micellaneous | ||||
| U49184 | -11.24 | -6.64 | -4.10 | occludin |
| L02950 | -5.26 | -4.49 | -3.85 | mu-crystallin |
| AB047079 | -2.20 | -2.54 | -4.21 | IRE1b |
| U29343 | -2.11 | -1.58 | -4.07 | hyaluronan receptor |
| D13633 | -2.21 | -1.72 | -6.35 | putative gene KIAA0008 |
| AF057557 | -1.75 | -3.43 | -3.45 | TOSO |
| X59350 | -1.95 | -1.06 | -3.43 | CD22 |
| AF053641 | -1.46 | -1.45 | -2.65 | CSE1 |
| AF274943 | -1.20 | -1.06 | -2.45 | PNAS-18 |
| M91438 | -1.18 | -1.02 | -3.41 | HUSI-II |