TABLE 3.

Change in prevalence and proportional abundance of taxa after circumcision

Phylum	Genus	Effect sizea	Adj. P-valueb	Prevalence (%)c		Median proportional abundance (%)
				Pre	Post	Pre	Post
Pseudomonadota	Campylobacter	−0.93	<0.0001	94	55	4.40	1.36
Bacillota	Peptoniphilus	−0.81	<0.0001	100	98	13.31	7.05
Actinomycetota	Varibaculum	−0.71	0.0001	100	92	7.09	3.28
Bacillota	Negativicoccus	−0.63	0.0001	61	22	1.21	0.00
Bacteroidota	Porphyromonas	−0.61	0.0002	94	88	5.84	2.94
Bacteroidota	Hoylesella	−0.59	0.0001	100	86	13.80	6.40
Bacillota	Ezakiella	−0.56	0.0010	92	80	7.09	3.04
Bacillota	Fastidiosipila	−0.52	0.0001	12	0	0.00	0.00
Actinomycetota	Arcanobacterium	−0.49	0.0001	16	0	0.00	0.00
Actinomycetota	Actinotignum	−0.49	0.0002	67	41	1.32	0.00
Actinomycetota	Corynebacterium	0.55	0.0003	84	98	2.66	7.80
Bacillota	Staphylococcus	0.87	<0.0001	88	96	3.52	21.75

^a Calculated using ALDEx2.

^b Benjamini-Hochberg-corrected P-values, calculated by Wilcoxon rank-sum test.

^c Genera were considered prevalent in individuals with >1% proportional abundance.