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. 2026 Apr 14;36(6):1183–1193. doi: 10.1038/s41370-026-00891-6

Table 2.

Characteristics of Childhood Acute Lymphoblastic Leukemia (ALL) Cases and Controls in Los Angeles County, California (2000–2015).

ALL Cases (n = 125) Controls (n = 219) P (χ2)1
Child’s birth year 0.99
2000–2004 50 (40.0%) 84 (38.4%)
2005–2009 43 (34.4%) 72 (32.9%)
2010–2015 32 (25.6%) 63 (28.7%)
Child’s age at blood collection (hours) 0.21
<24 30 (24.0%) 61 (27.8%)
≥24 & ≤48 73 (58.4%) 118 (53.9%)
>48 22 (17.6%) 38 (17.4%)
Missing 0 (0.0%) 2 (0.9%)
Child’s sex 0.07
Male 67 (53.6%) 99 (45.2%)
Female 58 (46.4%) 120 (54.8%)
Child’s race/ethnicity 0.33
White 22 (17.6%) 44 (20.1%)
Hispanic 92 (73.6%) 152 (69.4%)
Other or unknown 11 (8.8%) 23 (10.5%)
Birth order 0.62
First child 53 (42.4%) 88 (40.2%)
Second child 41 (32.8%) 70 (32.0%)
Third or more 31 (24.8%) 61 (27.9%)
Total children ever born 0.54
One 53 (42.4%) 87 (39.7%)
Two 40 (32.0%) 69 (31.5%)
Three 18 (14.4%) 39 (17.8%)
Four or more 14 (11.2%) 23 (10.5%)
Missing 0 (0.0%) 1 (0.5%)
Delivery method 0.83
Vaginal 87 (69.6%) 136 (62.1%)
Cesarean 38 (30.4%) 83 (37.9%)
History of miscarriage 0.61
No 106 (84.8%) 190 (86.7%)
Yes 19 (15.2%) 28 (12.8%)
Missing 0 (0.0%) 1 (0.5%)
Maternal age (years) 0.04
<25 36 (28.8%) 72 (32.9%)
≥25 & <35 65 (52.0%) 107 (48.9%)
≥35 24 (19.2%) 40 (18.3%)
Paternal age (years) 0.52
<25 18 (14.4%) 46 (21.0%)
≥25 & <35 55 (44.0%) 93 (42.5%)
≥35 52 (41.6%) 80 (36.5%)
Maternal education 0.32
High school or less 62 (49.6%) 120 (54.8%)
Some college or more 62 (49.6%) 94 (42.9%)
Missing 1 (0.8%) 5 (2.3%)
Paternal education 0.64
High school or less 58 (46.4%) 112 (51.1%)
Some college or more 55 (44.0%) 83 (37.9%)
Missing 12 (9.6%) 24 (11.0%)
Insurance for delivery 0.03
Private 73 (58.4%) 105 (47.9%)
Public 50 (40%) 102 (46.6%)
Other <5 12 (5.5%)
Mother’s country of birth 0.72
Mexico 24 (19.2%) 45 (20.5%)
US 50 states 74 (59.2%) 138 (63.0%)
Other countries 23 (18.4%) 24 (11.0%)
Unknown 4 (3.2%) 12 (5.5%)
Median census tract house value ($1000) 0.68
≥10.0 & <142.8 26 (20.8%) 53 (24.2%)
≥142.8 & <162.6 20 (16.0%) 53 (24.2%)
≥162.6 & <197.7 40 (32.0%) 53 (24.2%)
≥197.7 & ≤1000.0 38 (30.4%) 54 (24.7%)
Missing 1 (0.8%) 6 (2.7%)
Water district 0.85
Unexposed water district 73 (58.4%) 105 (47.9%)
CA Water Service East Los Angeles 13 (10.4%) 14 (6.4%)
City of Downey Water Department 7 (5.6%) 15 (6.8%)
Golden State Water Co—Norwalk 7 (5.6%) 12 (5.5%)
Montebello Land & Water Co 5 (4.0%) 11 (5.0%)
Orchard Dale Water District <5 6 (2.7%)
Park Water Co—Bellflower/Norwalk <5 11 (5.0%0
City of Pico Rivera Water Department <5 7 (3.2%)
Pico Water District <5 11 (5.0%)
Santa Clarita Water Division 5 (4.0%) 15 (6.8%)
Valencia Water Company <5 12 (5.5%)

p-values are from design-based ANOVA. Counts less than five for strata other than missing and unknown were suppressed.