Skip to main content
. 2005 Dec 5;102(50):18135–18140. doi: 10.1073/pnas.0507798102

Fig. 5.

Fig. 5.

PN2/AβPP affects the severity of intracerebral hemorrhage. (a) Mice were stereotaxically injected with collagenase in the caudate/putamen. Twenty-four hours later, the brain was removed and analyzed for hematoma as described in Methods. Stained brain sections are presented from Tg-rPF4/APP (Left), wild-type (Center), and AβPP KO (Right) mice. (b) Quantitation of hematoma volume from Tg-rPF4/APP mice (n = 12), wild-type mice (n = 14), and AβPP KO mice (n = 7) at 24 h. The data presented are the mean ± SD. *, P < 0.0001; **, P < 0.002. (c) Quantitation of hemoglobin levels in the hemorrhagic (H) and contralateral control (C) hemispheres from Tg-rPF4/APP mice (n = 7), wild-type mice (n = 15), and AβPP KO mice (n = 7) at 24 h. The data presented are the mean ± SD. *, P < 0.0005; **, P < 0.02.