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. 2026 Apr 15;17:1810159. doi: 10.3389/fendo.2026.1810159

Table 2.

Laboratory parameters of patients with early-stage (group 1) and advanced-stage (group 2) of DKD.

Laboratory features Group 1 Group 2 p
n = 28 n = 48
25(OH)D (ng/mL) 30.0 ± 8.0 26.3 ± 9.8 0.03
Glucose (mg/dL) 130.7 ± 40.2 161.6 ± 61.2 0.02
HbA1c (%) 7.9 ± 0.9 8.2 ± 1.3 0.17
Creatinine (mg/dL) 0.84 ± 0.24 1.4 ± 0.4 <0.001
GFR (CKD-EPI) (mL/min/1,73m²) 88.3 ± 17.4 51.2 ± 14.4 <0.001
Total cholesterol (mg/dL) 160.0 ± 46.2 187.2 ± 48.7 0.02
HDL (mg/dL) 40.6 ± 12.5 40.4 ± 10.5 0.93
LDL (mg/dL) 86.3 ± 35.3 100.8 ± 43.3 0.15
Triglycerides (mg/dL) 171.0 ± 84.9 233.6 ± 153.0 0.05
Mean albuminuria (mg/g) 105.0 ± 67.7 614.0 ± 585.0 <0.001
Mean albuminuria (log10) 1.9 ± 0.3 2.6 ± 0.5 <0.001

25(OH)D, 25-hydroxyvitamin D; HbA1c, Glycated hemoglobin; GFR, Glomerular Filtration Rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; HDL, High-density lipoprotein; LDL, Low-density lipoprotein.