Table 2.
Sensitivity Analysis of OS and PFS for TACE+D+C group vs. TACE+D group (TACE+D as reference group).
| Time | Group | Unadjusted HR (95%CI) |
P-value | Adjusted* HR (95%CI) |
P-value |
|---|---|---|---|---|---|
| OS | TACE+D a | ||||
| OS | TACE+D+C | 0.65 (0.45-0.94) | 0.025 | 0.35 (0.22-0.54) | <.001 |
| PFS | TACE+D a | ||||
| PFS | TACE+D+C | 0.57 (0.39-0.83) | 0.003 | 0.34 (0.21-0.53) | <.001 |
*Full covariates: Age, sex, Child-Pugh class, HBV, portal vein invasion, BCLC stage, albumin, AST, ECOG PS, PIVKA-II, AFP level, tumor size, number of lesions, number of TACE.
aAs a reference group for adjusting covariates. HR, hazard ratio; CI, confidence interval; OS, overall survival; PFS, Progression-free survival; TACE+D, Transarterial Chemoembolization combined with donafenib; TACE+D+C, Transarterial Chemoembolization combined with donafenib and camrelizumab; PSM, propensity score matching.