Table 3.

Synthesis of 2-amino-4H- pyran derivates ^a

Entry	Product	Structure	Time (min)	M.P (OC) [Refs]	Yield b
1	5a		25	175–177 [40]	96
2	5b		35	173–175 [40]	97
3	5c		30	190 − 188 [40]	98
4	5d		30	132 − 130 [41]	95
5	5e		25	134 − 132 [40]	96
6	5f		40	192 − 188 [40]	97
7	5 g		25	136 − 134 [42]	98
8	5 h		30	192 − 190 [42]	90
9	5i		25	170 − 168 [43]	96
10	6a		25	229 − 227 [32]	95
11	6b		10	210 − 208 [31]	90
12	6c		30	191 − 189 [32]	96
13	6d		40	139 − 137 [32]	88
14	6e		25	120 − 118 [32]	98
15	6f		25	242 − 240 [32]	94
16	6 g		25	230 − 228 [44]	96

^a: Aldehydes (1 mmol), dimedone (1 mmol), and ethyl acetoacetate (1 mmol), in the presence of the L-Glu-MPS (20 mg) in EtOH (10 ml). ^b Isolated yield,