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. 2026 Apr 28;21(1):e12. doi: 10.22037/iej.v21i1.48350

Table 1.

Search strategy and terms used to identify studies

Database Formula Results
PubMed ((( "Mineral trioxide aggregate*" [Title/Abstract] OR "MTA cement" [Title/Abstract] OR MT aggregate[Title/Abstract] OR aggregate ProRoot[Title/Abstract] OR OrthoMTA[Title/Abstract] OR RetroMTA[Title/Abstract] OR MTA-Fillapex[Title/Abstract] OR Biodentine[Title/Abstract] OR "CEM Cement" [Title/Abstract] OR "Calcium enriched mixture" [Title/Abstract] OR "Calcium silicate based cement" [Title/Abstract] OR CSC[Title/Abstract]) AND (Toxic*[Title/Abstract] OR Cytotoxicit*[Title/Abstract])) OR ((MTA[Title/Abstract] OR "Mineral trioxide aggregate" [Title/Abstract] OR Biodentine[Title/Abstract] OR "CEM Cement" [Title/Abstract] OR "Calcium enriched mixture" [Title/Abstract] OR "Calcium silicate based cement" [Title/Abstract] OR CSC[Title/Abstract]) AND (("Toxic Actions" [Mesh]) OR "toxicity" [Subheading]))) OR ((( "calcium-enriched mixture cement" [Supplementary Concept]) OR ("mineral trioxide aggregate" [Supplementary Concept])) AND (("Toxic Actions" [Mesh]) OR "toxicity" [Subheading])) 1928
Web of Science Toxic* OR Cytotoxicit* (Topic) and "Mineral trioxide aggregate*" OR "MTA cement" OR "MT aggregate" OR aggregate ProRoot OR OrthoMTA OR RetroMTA OR MTA-Fillapex OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC (Topic) 1181
Scopus ( TITLE-ABS-KEY ("mineral trioxide aggregate*" OR "mta cement" OR "mt aggregate" OR aggregate AND proroot OR orthomta OR retromta OR mta-fillapex OR Biodentine OR "cem cement" OR "calcium enriched mixture" OR "calcium silicate based cement" OR csc ) AND TITLE-ABS-KEY ( toxic* OR cytotoxicit* ) ) 1641
Cochrane (MTA OR "Mineral trioxide aggregate" OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC) AND (Toxic* OR Cytotoxicit*) in Title Abstract Keyword - (Word variations have been searched) 163 (1 Review, 162 Trials)
ProQuest (abstract("Mineral trioxide aggregate*" OR "MTA cement" OR "MT aggregate" OR aggregate ProRoot OR OrthoMTA OR RetroMTA OR MTA-Fillapex OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC) OR mainsubject("Mineral trioxide aggregate*" OR "MTA cement" OR "MT aggregate" OR aggregate ProRoot OR OrthoMTA OR RetroMTA OR MTA-Fillapex OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC) OR title("Mineral trioxide aggregate*" OR "MTA cement" OR "MT aggregate" OR aggregate ProRoot OR OrthoMTA OR RetroMTA OR MTA-Fillapex OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC)) AND (abstract(Toxic* OR Cytotoxicit*) OR mainsubject(Toxic* OR Cytotoxicit*) OR title(Toxic* OR Cytotoxicit*)) 305
Wiley "(MTA OR "Mineral trioxide aggregate" OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC) AND (Toxic* OR Cytotoxicit*)" in Abstract 206
Ovid (All Database included Embase) ((Mineral trioxide aggregate or MTA cement or MT aggregate or aggregate ProRoot or OrthoMTA or RetroMTA or MTA-Fillapex or Biodentine or CEM Cement or Calcium enriched mixture or Calcium silicate based cement or CSC).ab. or (Mineral trioxide aggregate or MTA cement or MT aggregate or aggregate ProRoot or OrthoMTA or RetroMTA or MTA-Fillapex or Biodentine or CEM Cement or Calcium enriched mixture or Calcium silicate based cement or CSC).ti. or (Mineral trioxide aggregate or MTA cement or MT aggregate or aggregate ProRoot or OrthoMTA or RetroMTA or MTA-Fillapex or Biodentine or CEM Cement or Calcium enriched mixture or Calcium silicate based cement or CSC).kf.) AND ((Toxic* or Cytotoxicit*).ab. or (Toxic* or Cytotoxicit*).ti. or (Toxic* or Cytotoxicit*).kf.)) 2580
Total= 8004; After deleting duplicated files= 5195

Main Syntax: (MTA OR "Mineral trioxide aggregate" OR Biodentine OR "CEM Cement" OR "Calcium enriched mixture" OR "Calcium silicate based cement" OR CSC) AND (Toxic* OR Cytotoxicit*)