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. 2026 May 4;14(5):e013906. doi: 10.1136/jitc-2025-013906

Table 2. Time to metastasis using multivariate Cox-regression.

Variable Unadjusted (UVA) Adjusted (MVA)
HR 95% CI P value HR 95% CI P value
Gleason Score
 9 1 1
 10 3.373 0.388 to 29.338 0.27 6.189 0.366 to 104.760 0.2
Stage
 IIIC 1 1
 IVA 4.181 0.339 to 51.518 0.26 5.411 0.295 to 99.348 0.25
 IVB 6.856 1.134 to 41.442 0.03 9.702 0.840 to 112.038 0.06
ADT length
 ≤18 months 1 1
 >18 months 2.225 0.445 to 11.116 0.33 2.664 0.280 to 25.301 0.39
Responder group
 Early 1 1
 Late 1.651 0.324 to 8.408 0.55 0.391 0.048 to 3.195 0.38
Ricketts risk group
 High 1
 Low 4.04 0.783 to 20.844 0.09 9.256 1.061 to 80.719 0.04

P values <0.05 are bold for significance.

ADT, androgen deprivation therapy; MVA, multivariable analysis; UVA, univariable analysis.