Chart 1. Recommendations for alpha-1 antitrypsin testing for patients with bronchiectasis in different guidelines or consensus.

Chalmers et al. 12	“Alpha-1 antitrypsin testing should not be performed routinely but should be considered in patients with suggestive clinical and radiological features such as basal emphysema or severe airflow obstruction.”
Pereira et al, 15	Alpha-1 antitrypsin testing is part of the recommended investigation in the algorithm for the diagnosis and etiologic investigation of bronchiectasis.
Hill et al. 13	“Consider testing for alpha 1 antitrypsin deficiency in patients with coexisting basal panacinar emphysema.”
Chang et al. 14	“consider the following: Alpha-1-antitrypsin levels if there is evidence of chronic obstructive pulmonary disease/emphysema”