Figure 2:
Differential cellular and humoral effects of RSV-vaccination in hemodialysis patients and immunosuppressed patients. Levels of pan-RSV-specific IgG and RSV-F-IgG, as well as percentages of RSV-specific CD4 T cells before (pre-) and 14 days after (post-) vaccination in (a) patients on intermittent hemodialysis (HD, n = 15) versus non-dialysis patients (non-HD, n = 60), and in (b) patients under medical maintenance immunosuppression (IS, n = 11) versus patients without medical immunosuppression (non IS, n = 64) including comparison of the fold increase on vaccination. Dots represent individual patients; lines represent medians and interquartile ranges; columns represent geometric means with 95% confidence intervals. P values were calculated from paired values using the Wilcoxon matched pairs test, P values for fold increases were calculated using the Mann–Whitney test. CD, cluster of differentiation; Ig, immunoglobulin.
