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. 2026 Mar 27;26:397. doi: 10.1186/s12872-026-05779-9

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© The Author(s) 2026

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Kaplan-Meier survival curves for 28-day overall survival across ACAG groups. Higher ACAG levels were associated with significantly lower survival rates (P < 0.0001). B ROC curves showing that ACAG is a better predictor of 28-day mortality compared to the anion gap, with a higher AUC (0.776 vs. 0.690, P < 2.22e-16)