Table 4.
Genotypes and frequencies of codon 72 p53 polymorphism variants in prostate carcinomas and hyperplasias.
p53 codon 72 allele | Prostate Carcinomas | Prostate Hyperplasias |
Arg/Arg | 20 (0.51) | 23 (0.48) |
Pro/Pro | 2 (0.05) | 2 (0.04) |
Pro/Arg | 17 (0.44) | 23 (0.48) |
Total | 39 | 48 |
The data are a summary of all experiments because identical results were obtained for each DNA with the two methods used for p53 allele typing (allele specific PCR, and PCR-RFLP), and no differences were observed between the two DNA sample sources (peripherical blood leucocytes or neoplastic tissue) from the individual patients.