Table 1.

Eye measurements (mean ± SD) in 29 subjects exposed to 1 mg/m³ 3-MF or clean air for 2 hr.

	Measured break-up time (sec)			Self-reported break-up time (sec)
Exposure	Before	Aftera	4 hr afterb	Before	Aftera	4 hr afterb	Blinking frequency during exposurec	Lissamine staining after exposured
Air	36 ± 19	−3 ± 17	−3 ± 17	32 ± 19	3 ± 17	3 ± 14	5.8 ± 0.7	0.2 ± 0.3
3-MF	33 ± 21	6 ± 8*	−1 ± 16	35 ± 21	2 ± 20	−4 ± 19	7.6 ± 0.8**	0.3 ± 0.5

^aEnd of exposure compared with before exposure; negative value indicates decrease.

^bFour hours after exposure compared with before exposure; negative value indicates decrease.

^cBlinking frequency (blinks per minute) during exposure.

^dEpithelial damage score (0–9), measured by lissamine staining, 4 hr after exposure.

^*p = 0.014 by Wilcoxon rank sum test.

^**p < 0.001 by repeated-measures ANOVA.