Table 2.

Study characteristics, geriatric settings

Study authors	Year	Country	Setting	Design	No. of patients	Age in years	Gender	VTE occurrence rate	Diagnosis as a risk	Medication as a risk	Mobility as a risk	Risk assessment/ screening	Prophylaxis	Added comments
Kleijer et al23	2010	The Netherlands	Record on community pharmacies on in-patient admissions	A case–control study nested within cohort of psychiatric patients	1031 Cases and 4125 control	76 (60–104)	43% female	0.90%	Not mentioned	No association with antipsychotics, or type or 5HT affinity	Not recorded	Included patients with VTE	Not recorded	Current use of antipsychotics was not associated with the risk of VTE in a nested cohort study of around 111 818 patients
Weill Engerer et al26	2004	France	Geriatric unit	A prospective case–control study	310 Cases and 310 controls	85.7 ± 7.0	75% Female	Not calculated	Not mentioned	Not mentioned	Increased duration and the type of immobility (settings)	Not reported (included symptomatic patients)	Not reported	VTE incidence higher in acute in-patient settings compared with long-term units. Odds of VTE increases 1.5-fold over 10 years. Restriction of mobility; both the type and duration of immobility were associated with patients developing VTE
Gallerani et al24	2012	Italy	Geriatric unit	Case series	4	Mean age 78.2 years	3 females	0.66% Pulmonary embolism	Not mentioned	Risperidone associated with risk of pulmonary embolism	Not mentioned	All patients had VTE	Not mentioned

VTE, venous thromboembolism; 5HT, 5Hydroxy tryptophan.