2. Synthesis of 8 from Grob Fragmentation of α-Diketone 5: (a) TFA, 1,2-DCE, Reflux, 1 h; (b) CH2N2–Et2O, MeOH, 0 °C, 0.5 h; (c) K2CO3, BnBr, Acetone, 0 °C-rt, 36 h, 87% (3 Steps).
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.