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Forest plot and risk-of-bias assessment of biomarker-guided antibiotic treatment for SAP incidence. Risk of bias legend: (A) bias arising from the randomization process, (B) bias due to deviations from intended interventions, (C) bias due to missing outcome data, (D) bias in measurement of the outcome, (E) bias in selection of the reported result, (F) overall bias. 
High, 
some concerns, 
low, 
No information.
