Table 5.

Meta-analysis of the performance of biomarkers for SAP risk prediction in external validation.

	Number of Studies Included	ROC	SE	95% CI	Q	I2	Egger’s test
NLR	8 (35,55,56,74,84,86,87,90)	0.803	0.0246	0.755 to 0.852	80.1075	91.26%	0.0184
CRP	7 (34,35,42,50,56,69,73)	0.800	0.0295	0.742 to 0.858	67.1831	91.07%	0.2704
Il-6	4 (69,76–78)	0.808	0.0327	0.744 to 0.872	8.2440	63.61%	0.1570
Neutrophiles	4 (35,56,73,82)	0.787	0.0326	0.723 to 0.851	39.8361	92.47%	0.0031

Abbreviations: CRP = C-Reactive Protein; IL-6 = Interleukin-6; I² = I-squared; NLR = neutrophil-to-lymphocyte ratio; Q = Cochran’s Q; ROC = receiver operating characteristic.