Figure 7.
Effect of ICI on genistein-induced uterine CaBP-9k protein expression. Immature rats were injected SC with ICI at 30 min prior to genistein (40 mg/kg BW per day) or E2, and euthanized 24 h after final injection. The level of CaBP-9k protein was analyzed by immunoblot analysis. The values represent means ± SD. a, P < 0.05 vs. vehicle; b, P < 0.05 vs. genistein or E2 treatment only [Reproduced with permission from Lee GS, Choi KC, Kim HJ, Jeung EB 2004 Effect of genistein on the expression of Calbindin-D9k as a potential estrogenic compound in the uterus of immature rats through estrogen receptors. Toxicol Sci 82: 451–457]