Table 4.

Antioxidant parameters in healthy volunteers after regular consumption of native or dealcoholized red wine

	RW	DRW	Controls
Subjects, n	24	25	25
Parameter
TPP, mg CE/L
Baseline	15.6 ± 1.6	15.6 ± 2.1	15.5 ± 1.4
6 wk	16.4 ± 1.4*	16.0 ± 2.0	15.3 ± 2.2
TEAC, mmol/L
Baseline	1.47 ± 0.06	1.44 ± 0.08	1.46 ± 0.08
6 wk	1.45 ± 0.04	1.42 ± 0.07	1.43 ± 0.07
Vitamin C, mg/dL
Baseline	1.30 ± 0.28	1.43 ± 0.36	1.48 ± 0.29
6 wk	1.35 ± 0.26	1.42 ± 0.39	1.57 ± 0.28
α-Tocopherol, mg/dL
Baseline	11.3 ± 3.0	11.2 ± 2.6	11.2 ± 2.9
6 wk	11.3 ± 3.0	11.5 ± 2.7	11.0 ± 2.7
Uric acid, mg/dL
Baseline	4.7 ± 1.2	4.4 ± 1.1	4.4 ± 1.2
6 wk	4.9 ± 1.2	4.5 ± 0.9	4.7 ± 1.5*
Albumin, g/dL
Baseline	4.2 ± 0.4	4.3 ± 0.4	4.2 ± 0.4
6 wk	4.3 ± 0.4	4.1 ± 0.6	4.2 ± 0.5
Bilirubin, mg/dL
Baseline	0.68 ± 0.28	0.68 ± 0.33	0.64 ± 0.33
6 wk	0.61 ± 0.35	0.59 ± 0.27*	0.62 ± 0.35
TM0, arbitrary units
Baseline	2,18 ± 0,56	1,97 ± 0,56	2,22 ± 0,79
6 wk	1,88 ± 0,48*	2,05 ± 0,70	1,95 ± 0,49
TM300, arbitrary units
Baseline	1,02 ± 0,69	0,87 ± 0,72	0,95 ± 0,54
6 wk	0,96 ± 0,49	0,92 ± 0,65	1,18 ± 0,50

Amounts ingested daily for 6 weeks were 200 mL red wine (RW) or 175 mL dealcoholized red wine (DRW). Control subjects did not receive any study drink.

TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM₀: Tail Moment in untreated cells (endogenous DNA strand breaks);

TM₃₀₀: Tail Moment in cells treated with 300 μM H₂O₂ for 20 min (exogenous DNA strand breaks)

Values are means ± SD

*Values different from baseline, P < 0.05 by Wilcoxon signed rank test