TABLE 2.
Peri-sedation outcomes.
| Variables | Total (n = 180) | Group D+C (n = 90) | Group D+M (n = 90) | P |
|---|---|---|---|---|
| First-attempt sedation success, n (%) | 164 (91.11) | 78 (86.67) | 86 (95.56) | 0.036 |
| Sedation onset time (min), M (Q1, Q3) | 20.50 (15.75, 26.00) | 18.50 (15.00, 23.00) | 23.00 (18.00, 30.00) | <0.001 |
| Procedure duration (min), M (Q1, Q3) | 68.00 (63.00, 80.00) | 68.00 (64.00, 77.75) | 68.00 (62.25, 80.75) | 0.544 |
| Recovery time (min), M (Q1, Q3) | 27.00 (19.00, 35.00) | 30.50 (20.25, 37.00) | 26.00 (16.25, 34.00) | 0.052 |
| Bradycardia, n (%) | 19 (10.56) | 12 (13.33) | 7 (7.78) | 0.225 |
| Respiratory depression, n (%) | 10 (5.56) | 6 (6.67) | 4 (4.44) | 0.515 |
| Hypoxemia, n (%) | 6 (3.33) | 4 (4.44) | 2 (2.22) | 0.678 |
| Nausea and vomiting, n (%) | 5 (2.78) | 4 (4.44) | 1 (1.11) | 0.364 |
| Delayed recovery | 1 (0.56) | 1 (1.11) | 0 (0.00) | 1.000 |
| Children’s medication acceptance, M (Q1, Q3) | 4.00 (4.00, 4.00) | 4.00 (3.00, 4.00) | 4.00 (4.00, 5.00) | <0.001 |
| Parental satisfaction, M (Q1, Q3) | 4.00 (4.00, 4.00) | 4.00 (4.00, 4.00) | 4.00 (4.00, 5.00) | <0.001 |
Data are presented as median (interquartile range) or number (%), as appropriate.
Abbreviations: Group D+C received intranasal dexmedetomidine combined with oral chloral hydrate, and Group D+M received intranasal dexmedetomidine combined with oral midazolam.