Fig. 4.

Plasma exosomal FAP is elevated in SLE patients and correlates with disease activity. A-C Plasma exosomal FAP levels measured by nano-flow cytometry in the NC, SLE, N-SLE, and RA groups (NC group, n=11; SLE group, n=11; N-SLE group, n=13; RA group, n=11). D Correlation analysis of plasma exosomal FAP levels with clinical indices in SLE patients, including SLEDAI, anti-dsDNA antibody, C3, and C4 (SLEDAI, n=24; anti-dsDNA, n=12; C3, n=23; C4, n=23; CRP, n=20; ESR, n=24; WBC, n=24; PLT, n=24; IgG, n=23; PRO, n=22; mALB, n=11; β2-mg, n=11). *, P < 0.05; ****, P < 0.0001; ns, no statistical significance