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. 2005 Dec 17;331(7530):1431–1437. doi: 10.1136/bmj.38643.368692.68

Table 2.

Annual costs in international dollars ($Int),* infections averted, DALYs averted, and average cost effectiveness for various single interventions to control HIV/AIDS in Sear-D region, compared with no intervention

Intervention Coverage level Yearly costs ($Int, millions) Yearly infections averted (millions) Average cost effectiveness ratio ($Int/infection averted) Yearly DALYs averted (millions) Average cost effectiveness ratio ($Int/DALY averted)
Mass media 100% 33 0.11 309 1.8 18
Peer education for sex workers 50%
78
1.49
53
24.6
3
80%
115
2.20
52
36.1
3
95% 133 2.49 53 40.9 3
Peer education and treatment of sexually transmitted infections for sex workers
50%
83
1.82
45
29.9
3
80%
122
2.57
47
42.1
3
95%
141
2.85
50
46.6
3
School based education 50%
174
0.01
13 326
0.2
790
80%
175
0.02
8544
0.3
506
95% 176 0.02 7288 0.4 432
Voluntary counselling and testing 95% 207 0.32 642 5.2 40
Prevention of mother to child transmission ANC 268 0.04 7191 0.9 310
Treatment of sexually transmitted infections Current 177 0.34 522 5.6 32
ANC
297
0.66
448
10.9
27
95% 356 1.08 330 17.7 20
Antiretroviral therapy:
No intensive monitoring, first line drugs only ANC 550 0.03 18 884 1.0 542
Intensive monitoring, first line drugs only ANC 588 0.03 21 788 1.0 570
No intensive monitoring, first and second line drugs ANC 1671 0.03 56 718 1.3 1319
Intensive monitoring, first and second line drugs ANC 1774 0.03 55 188 1.4 1280

ANC=antenatal care coverage level.

*

International dollars are a hypothetical unit of currency that has the same purchasing power that the US$ has in the United States at a given point in time. Details of this approach are discussed elsewhere.12

Intervention benefits are not comparable with current epidemiological estimates because results in this analysis are computed in relation to a “no intervention” comparator, which subtracts current levels of condom use, treatment of sexually transmitted infections, and antiretroviral treatment.