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. Author manuscript; available in PMC: 2026 May 10.
Published in final edited form as: INNOSC Theranostics Pharmacol Sci. 2025 Jul 1;8(3):71–84. doi: 10.36922/itps025080007

Table 2.

Genomic analysis of Klebsiella pneumoniae cells in the control group

Position Frequency (%) Annotation Gene Product
2,228,365 69.2 Intergenic (−35/−67) sfaA/sfaD Staphyloferrin A export MFS transporter/
D-ornithine citrate ligase
1,700,478 65.6 G59S* (GGC→AGC) KQ76_RS08360 Adenine phosphoribosyltransferase
1,017,325 65.3 Q304* (CAA→TAA) fmtA Teichoic acid D-alanine esterase
342,330 62.0 I180I* (ATT→ATC) KQ76_RS01520 DUF3169 family protein
2,574,726 32.2 G69A* (GGC→GCC) KQ76_RS13020 Alpha/beta hydrolase
2,389,192 32.0 R188P* (CGA→CCA) hssR DNA-binding heme response regulator
1,213,003 31.3 E184D* (GAG→GAC) ylqF Ribosome biogenesis GTPase
860,322 31.3 E344K* (GAA→AAA) dltB Peptidoglycan teichoic acid
D-alanyltransferase
2,252,747 29.9 Intergenic (−54/+157) KQ76_RS11280/KQ76_RS11285 M23 family metallopeptidase/haloacid
dehalogenase-like hydrolase subfamily IIB
391,361 29.1 S36I *(AGT→ATT) KQ76_RS01815 General stress protein
810,694 29.0 M1K* (ATG→AAG) smpB SsrA-binding protein
1,536,460 27.5 Y112* (TAT→TAA) KQ76_RS07375 Phage major capsid protein
1,027,271 27.0 A87P* (GCA→CCA) purS Phosphoribosylformylglycinamidine
synthase subunit
2,776,116 26.7 H117Q* (CAT→CAA) mnmG tRNA uridine
5-carboxymethylaminomethyl (34)
synthesis enzyme
2,574,727 26.6 G69R* (GGC→CGC) KQ76_RS13020 Alpha/beta hydrolase
2,564,194 26.6 A17P* (GCA→CCA) KQ76_RS12955 D-lactate dehydrogenase
2,190,680 25.7 T500S* (ACG→TCG) KQ76_RS10985 BglG family transcriptional antiterminator

Notes: Asterisk (*) indicates that the annotation provides functional context to the corresponding gene sequence, facilitating interpretation and analysis; Underlined letters denote specific nucleotide or amino acid mutations identified within the sequence.

Abbreviations: BglG: Beta-glucoside operon antiterminator protein; GTP: Guanosine triphosphate; MFS: Major facilitator superfamily; SsrA: Small stable RNA A; tRNA: Transfer RNA.