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. Author manuscript; available in PMC: 2026 May 10.
Published in final edited form as: INNOSC Theranostics Pharmacol Sci. 2025 Jul 1;8(3):71–84. doi: 10.36922/itps025080007

Table 4.

Genomic analysis of Escherichia coli cells in the control group

Position Frequency (%) Annotation Gene Product
5,022,977 35.4 L28V* (CTC→GTC) pqiB Intermembrane transport protein PqiB
82,367 29.6 A100P* (GCC→CCC) mdoG Glucan biosynthesis protein G
5,022,975 29.2 A27G* (GCG→GGG) pqiB Intermembrane transport protein PqiB
4,935,212 28.6 Intergenic (−362/+132) lysO/aqpZ L-lysine exporter LysO/aquaporin Z
325,706 27.4 S9R* (AGC→AGG) sirB2 Invasion regulator SirB2
1,664,261 27.1 T163T* (ACC→ACG) fryC PTS fructose transporter subunit IIC
1,244,541 26.2 V392L* (GTA→CTA) hisD Histidinol dehydrogenase
1,078,228 25.0 A53P* (GCC→CCC) D1792_RS05680 DUF4756 family protein
2,077,731 24.0 Intergenic (−7/+65) D1792_RS10070/D1792_RS10075 Phosphoglycerate dehydrogenase/SIS domain-containing protein
2,376,513 23.8 G116G* (GGC→GGA) D1792_RS11465 YtfJ family protein
2,725,980 22.5 G94G* (GGC→GGG) chiA Bifunctional chitinase/lysozyme
2,936,459 21.8 L94* (TTA→TGA) ‡ rcdB LysR family transcriptional regulator
2,555,115 21.5 V98L* (GTG→CTG) diaA DnaA initiator-associating protein DiaA
2,077,733 20.0 Intergenic (−9/+63) D1792_RS10070/D1792_RS10075 Phosphoglycerate dehydrogenase/SIS domain-containing protein

Note: Asterisk (*) indicates that the annotation provides functional context to the corresponding gene sequence, facilitating interpretation and analysis; Double dagger (‡) indicates a variant that is flagged as potentially problematic or requires further investigation; Underlined letters denote specific nucleotide or amino acid mutations identified within the sequence.

Abbreviations: PTS: Phosphotransferase system; PqiB: Paraquat-inducible protein B; SirB2: Signal regulatory protein beta 2; SIS: Sugar isomerase.