Table 1.
Requirement for components of the GSH–glutaredoxin and thioredoxin systems
| Genotype | Viability |
|---|---|
| glr1 trx1 trx2 | Non-viable1 |
| trx1 trx2 grx1 grx2 | Non-viable2 |
| gsh1 trx1 | Viable |
| gsh1 trx2 | Viable |
| gsh1 trx1 trx2 | Non-viable |
| gsh1 glr1 | Viable |
| trr1 glr1 | Non-viable |
| trr1 trx1 | Viable |
| trr1 trx2 | Viable |
| trr1 trx1 trx2 | Viable |
Yeast genetic analysis was used to determine the viability of mutants lacking multiple components of the GSH–glutaredoxin and thioredoxin systems.
1From Muller (1996).
2From Draculic et al. (2000).