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Ovine raft cultures. The rafts were infected with orf virus after 6 days of differentiation and treated with various concentrations (50, 20, 5, and 2 μg/ml) of HPMPC. At 11 days of differentiation, the rafts were fixed and stained with hematoxylin-eosin. Magnifications, ×9 and ×36 in the right and left panels, respectively.
