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Inhibitory activity of N-MCT-TP, CDV-DP, and GCV-TP on in vitro DNA synthesis, mediated by recombinant KSHV polymerase and polymerase processivity factor, depicted as % inhibition (mean ± standard deviation of triplicate wells). Shown in the inset are IC50 values (means ±standard deviations) from three independent experiments for each compound. Compounds: (▪) N-MCT-TP; (▵) CDV-DP; (•) GCV-TP.
