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Antimalarial activity against Plasmodium falciparum cell lines
| Compound no. | IC50 (ng/ml) for parasite clonea:
|
|||
|---|---|---|---|---|
| D-6 | W-2 | RCS | TM91C235 | |
| 1 | 0.0191 | 0.4453 | 0.3569 | 1.2178 |
| 2a | 7.9727 | 127.80 | >250 | >250 |
| 2b | >250 | >250 | >250 | >250 |
| 3a | 0.0236 | 0.0752 | 0.0236 | 0.0845 |
| 3b | 0.0101 | 0.0183 | 0.0116 | 0.0212 |
| 3c | 0.1284 | 0.1284 | 0.2571 | 0.4021 |
| 4 | 27.2403 | 53.9027 | 83.3969 | |
| 5 | 46.033 | 104.0182 | ||
D-6, CDC Sierra Leone I; W-2, CDC Indochina III; RCS, isolates from Brazil; TM91C235, Southeast Asia isolates.
