TABLE 4.
Antimalarial activity of compound 3a against P. yoelii
| Compound no. or drug | Oral dose (mg/kg) | No. of mice cured/total no. of mice |
|---|---|---|
| 3a | 40 | 5/5 |
| 10 | 5/5 | |
| 2.5 | 5/5 | |
| 0.625 | 5/5 | |
| 0.3125 | 4/5 | |
| 0.15625 | 4/5 | |
| Tafenoquine | 10 | 5/5 |
| 5 | 5/5 | |
| 2.5 | 4/5 | |
| 1.25 | 2/5 |
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