TABLE 1.

Rate of plasmid loss calculated from the data in Fig. 6 and the rates observed for two control plasmids lacking replication origins (pEGFP-C1 and pd1EGFP-N1; Clontech)^a

Construct	Series	Rate of loss per cell generation (%)
pMMEG	1	5.5
pMMEG	2	6.5
pMMEG*	1	6.6
pMMEG*	2	5.9
pFRG*	1	13.1
pFRG*	2	13.6
Control plasmids
pEGFP-C1		21.7
pdEGFP-N1		29.8

^aThe experiment was performed twice (series 1 and 2).