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. 2005 Dec;79(24):15388–15397. doi: 10.1128/JVI.79.24.15388-15397.2005

FIG. 6.

FIG. 6.

Thapsigargin and CLT inhibit virion maturation. HCMV-infected HFF cells were treated with DMSO (A and D), thapsigargin (Thap) (B and E), or CLT (C and F) at 72 hpi and harvested at 96 hpi for analysis by electron microscopy. Panels D, E, and F show higher-magnification images of panels A, B, and C, respectively. Arrows indicate properly formed virions in the control samples (panels A and D) and abnormal clustering and formation of virions and tegument bodies in thapsigargin- and CLT-treated cells (panels B, C, E, and F). Scales are shown below the left and right sets of panels (panels A to C and D to F, respectively).